DOI: 10.1002/jrs.1534. Immuno‐Raman microspectroscopy: <i>In situ</i> detection of antigens in tissue specimens by surface‐enhanced Raman scattering

Immuno‐Raman microspectroscopy: In situ detection of antigens in tissue specimens by surface‐enhanced Raman scattering

10.1002/jrs.1534

Crossref journal-article

Wiley

Journal of Raman Spectroscopy (311)

Abstract

AbstractWe demonstrate the first realization of immuno‐Raman microspectroscopy, a novel methodology in immunohistochemistry. The in situ detection of antigens in tissue specimens is achieved by surface‐enhanced Raman scattering (SERS) from aromatic Raman labels covalently linked to the corresponding antibody. As an example of applications of this new Raman technique, we present the localization of prostate‐specific antigen (PSA) in epithelial tissue from patients with prostate carcinoma (PCA). Copyright © 2006 John Wiley & Sons, Ltd.

Bibliography

SchlÃ¼cker, S., KÃ¼stner, B., Punge, A., Bonfig, R., Marx, A., & StrÃ¶bel, P. (2006). ImmunoâRaman microspectroscopy: In situ detection of antigens in tissue specimens by surfaceâenhanced Raman scattering. Journal of Raman Spectroscopy, 37(7), 719â721. Portico.

Authors 6

S. Schlücker (first)
B. Küstner (additional)
A. Punge (additional)
R. Bonfig (additional)
A. Marx (additional)
P. Ströbel (additional)

References 6 Referenced 131

{'key': 'e_1_2_1_2_2', 'volume-title': 'Microscopy, Immunohistochemistry, and Antigen Retrieval Methods', 'author': 'Hayat MA', 'year': '2002'} / Microscopy, Immunohistochemistry, and Antigen Retrieval Methods by Hayat MA (2002)
10.1016/S0022-5347(05)68543-6
10.1021/ac034356f
10.1021/nl025531v
10.1021/ac0258352
10.1039/a605347e

Dates

Type	When
Created	19 years, 4 months ago (April 10, 2006, 6:46 a.m.)
Deposited	1 year, 9 months ago (Nov. 15, 2023, 1:27 a.m.)
Indexed	4 months, 1 week ago (April 23, 2025, 1:45 p.m.)
Issued	19 years, 4 months ago (April 10, 2006)
Published	19 years, 4 months ago (April 10, 2006)
Published Online	19 years, 4 months ago (April 10, 2006)
Published Print	19 years, 2 months ago (July 1, 2006)

Funders 0

None

BibTeX

@article{Schl_cker_2006, title={Immuno‐Raman microspectroscopy: In situ detection of antigens in tissue specimens by surface‐enhanced Raman scattering}, volume={37}, ISSN={1097-4555}, url={http://dx.doi.org/10.1002/jrs.1534}, DOI={10.1002/jrs.1534}, number={7}, journal={Journal of Raman Spectroscopy}, publisher={Wiley}, author={Schlücker, S. and Küstner, B. and Punge, A. and Bonfig, R. and Marx, A. and Ströbel, P.}, year={2006}, month=apr, pages={719–721} }

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