DOI: 10.1002/jmri.10243. MRI measurement of time‐resolved wall shear stress vectors in a carotid bifurcation model, and comparison with CFD predictions

MRI measurement of time‐resolved wall shear stress vectors in a carotid bifurcation model, and comparison with CFD predictions

10.1002/jmri.10243

Crossref journal-article

Wiley

Journal of Magnetic Resonance Imaging (311)

Abstract

AbstractPurposeTo study pulsatile fluid flow in a physiologically realistic model of the human carotid bifurcation, and to derive wall shear stress (WSS) vectors.Materials and MethodsWSS vectors were calculated from time‐resolved 3D phase‐contrast (PC) MRI measurements of the velocity field. The technique was first validated with sinusoidal flow in a straight tube, and then used in a model of a healthy human carotid bifurcation. Velocity measurements in the inflow and outflow regions were also used as boundary conditions for computational fluid dynamics (CFD) calculations of WSS, which were compared with those derived from MRI alone.ResultsThe straight tube measurements gave WSS results that were within 15% of the theoretical value. WSS results for the phantom showed the main features expected from fluid dynamics, notably the low values in the bulb region of the internal carotid artery, with a return to ordered flow further downstream. MRI was not able to detect the high WSS values along the divider wall that were predicted by the CFD model. Otherwise, there was good general agreement between MRI and CFD.ConclusionThis is the first report of time‐resolved WSS vectors estimated from 3D‐MRI data. The technique worked well except in regions of disturbed flow, where the combination with CFD modeling is clearly advantageous. J. Magn. Reson. Imaging 2003;17:153–162. © 2003 Wiley‐Liss, Inc.

Bibliography

Papathanasopoulou, P., Zhao, S., KÃ¶hler, U., Robertson, M. B., Long, Q., Hoskins, P., Yun Xu, X., & Marshall, I. (2003). MRI measurement of timeâresolved wall shear stress vectors in a carotid bifurcation model, and comparison with CFD predictions. Journal of Magnetic Resonance Imaging, 17(2), 153â162. Portico.

Authors 8

Panorea Papathanasopoulou (first)
Shunzhi Zhao (additional)
Uwe Köhler (additional)
Malcolm B. Robertson (additional)
Quan Long (additional)
Peter Hoskins (additional)
X. Yun Xu (additional)
Ian Marshall (additional)

References 28 Referenced 148

{'key': 'e_1_2_6_2_2', 'first-page': '293', 'article-title': 'Pulsatile flow and atherosclerosis in the human carotid bifurcation—positive correlation between plaque location and low and oscillating shear stress', 'volume': '5', 'author': 'Ku DN', 'year': '1985', 'journal-title': 'Atherosclerosis'} / Atherosclerosis / Pulsatile flow and atherosclerosis in the human carotid bifurcation—positive correlation between plaque location and low and oscillating shear stress by Ku DN (1985)
{'key': 'e_1_2_6_3_2', 'first-page': '1018', 'article-title': 'Haemodynamics and atherosclerosis—insights and perspectives gained from studies of human arteries', 'volume': '112', 'author': 'Glagov S', 'year': '1988', 'journal-title': 'Arch Pathol Lab Med'} / Arch Pathol Lab Med / Haemodynamics and atherosclerosis—insights and perspectives gained from studies of human arteries by Glagov S (1988)
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{'key': 'e_1_2_6_11_2', 'first-page': '237', 'article-title': 'In vitro and in vivo comparison of three MR measurement methods for calculating vascular shear stress in the internal carotid artery', 'volume': '20', 'author': 'Masaryk AM', 'year': '1999', 'journal-title': 'Am J Neuroradiol'} / Am J Neuroradiol / In vitro and in vivo comparison of three MR measurement methods for calculating vascular shear stress in the internal carotid artery by Masaryk AM (1999)
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{'issue': '1', 'key': 'e_1_2_6_19_2', 'first-page': '157', 'article-title': 'Fully automated PC‐MRA flow detection using phase and magnitude information: in vitro', 'volume': '8', 'author': 'Köhler U', 'year': '1999', 'journal-title': 'Magn Reson Materials in Physics, Biol and Med'} / Magn Reson Materials in Physics, Biol and Med / Fully automated PC‐MRA flow detection using phase and magnitude information: in vitro by Köhler U (1999)
{'issue': '1', 'key': 'e_1_2_6_20_2', 'first-page': '240', 'article-title': 'Segmented fifth‐order fit of 3D PC‐MRI flow data', 'volume': '11', 'author': 'Köhler U', 'year': '2000', 'journal-title': 'Magn Reson Materials in Physics, Biol and Med'} / Magn Reson Materials in Physics, Biol and Med / Segmented fifth‐order fit of 3D PC‐MRI flow data by Köhler U (2000)
{'issue': '1', 'key': 'e_1_2_6_21_2', 'first-page': '241', 'article-title': 'Calculation of the wall shear stress vector from 3D PC‐MRI flow data', 'volume': '11', 'author': 'Köhler U', 'year': '2000', 'journal-title': 'Magn Reson Materials in Physics, Biol and Med'} / Magn Reson Materials in Physics, Biol and Med / Calculation of the wall shear stress vector from 3D PC‐MRI flow data by Köhler U (2000)
{'key': 'e_1_2_6_22_2', 'first-page': '688', 'volume-title': 'Introduction to theoretical and computational fluid dynamics', 'author': 'Pozrikidis C', 'year': '1997'} / Introduction to theoretical and computational fluid dynamics by Pozrikidis C (1997)
{'key': 'e_1_2_6_23_2', 'first-page': '730', 'volume-title': 'Mechanics of fluids', 'author': 'Massey B', 'year': '1998'} / Mechanics of fluids by Massey B (1998)
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{'volume-title': 'CFDS‐CFX4.2 user manual, AEA industrial technology', 'year': '1997', 'key': 'e_1_2_6_25_2'} / CFDS‐CFX4.2 user manual, AEA industrial technology (1997)
{'key': 'e_1_2_6_26_2', 'first-page': '31', 'article-title': 'Flow in the larger arteries and its relation to the oscillatory pressure', 'volume': '124', 'author': 'Womersley JR', 'year': '1954', 'journal-title': 'J Physiol'} / J Physiol / Flow in the larger arteries and its relation to the oscillatory pressure by Womersley JR (1954)
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10.1016/S0021-9290(97)00125-5

Dates

Type	When
Created	22 years, 6 months ago (Jan. 23, 2003, 8:57 a.m.)
Deposited	1 year, 10 months ago (Oct. 9, 2023, 10:03 p.m.)
Indexed	1 month, 2 weeks ago (July 5, 2025, 8:33 p.m.)
Issued	22 years, 6 months ago (Jan. 22, 2003)
Published	22 years, 6 months ago (Jan. 22, 2003)
Published Online	22 years, 6 months ago (Jan. 22, 2003)
Published Print	22 years, 6 months ago (Feb. 1, 2003)

Funders 1

Engineering and Physical Sciences Research Council (EPSRC) 10.13039/501100000266 Engineering and Physical Sciences Research Council
Region: Europe
gov (National government)
Labels4
1. UKRI Engineering and Physical Sciences Research Council
2. Engineering and Physical Sciences Research Council - UKRI
3. Engineering & Physical Sciences Research Council
4. EPSRC

BibTeX

@article{Papathanasopoulou_2003, title={MRI measurement of time‐resolved wall shear stress vectors in a carotid bifurcation model, and comparison with CFD predictions}, volume={17}, ISSN={1522-2586}, url={http://dx.doi.org/10.1002/jmri.10243}, DOI={10.1002/jmri.10243}, number={2}, journal={Journal of Magnetic Resonance Imaging}, publisher={Wiley}, author={Papathanasopoulou, Panorea and Zhao, Shunzhi and Köhler, Uwe and Robertson, Malcolm B. and Long, Quan and Hoskins, Peter and Yun Xu, X. and Marshall, Ian}, year={2003}, month=jan, pages={153–162} }

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