DOI: 10.1002/jez.1401800205. A histological study of the early stages of cutaneous wound healing in lizards in <i>in vivo</i> and <i>in vitro</i>

A histological study of the early stages of cutaneous wound healing in lizards in in vivo and in vitro

10.1002/jez.1401800205

Crossref journal-article

Wiley

Journal of Experimental Zoology (311)

Abstract

AbstractThe responses of the skin to wounding from six hours to ten days have been studied histologically in a variety of lizard species. Whatever the size of the initial wound, all aspects of cutaneous structure, i.e., general scale architecture, epidermal cell activity, and epidermal specializations, are disrupted by a sequence of cellular events quite distinct from those described in other vertebrates. The epidermis on either side of the incision dies along a variable length, and epithelial migration occurs along a prepared hypercellular path through the dermis where the normal collagen fibers are destroyed. A segment of apparently physically undamaged tissue is discarded from the body surface and the subjacent “wound epidermis” undergoes rapid cell proliferation and maturation leading to the formation of a hyperplastic cornified tissue whose cells resemble the normal α‐layer, but which shows no indication of the typical epidermal generation structure.

Bibliography

Maderson, P. F. A., & Roth, S. I. (1972). A histological study of the early stages of cutaneous wound healing in lizards in in vivo and in vitro. Journal of Experimental Zoology, 180(2), 175â185. Portico.

Authors 2

P. F. A. Maderson (first)
S. I. Roth (additional)

References 15 Referenced 25

10.1002/jez.1401740211
{'key': 'e_1_2_1_3_1', 'first-page': '366', 'volume-title': 'Repair and Regeneration: The Scientific Basis for Surgical Practice', 'author': 'Dunphy J. E.', 'year': '1969'} / Repair and Regeneration: The Scientific Basis for Surgical Practice by Dunphy J. E. (1969)
10.1016/0012-1606(68)90046-8
{'key': 'e_1_2_1_5_1', 'first-page': '366', 'volume-title': 'Repair and Regeneration: The Scientific Basis for Surgical Practice', 'author': 'Giacommetti L.', 'year': '1969'} / Repair and Regeneration: The Scientific Basis for Surgical Practice by Giacommetti L. (1969)
{'key': 'e_1_2_1_6_1', 'first-page': '151', 'article-title': 'The skin of snakes and lizards', 'volume': '3', 'author': 'Maderson P. F. A.', 'year': '1964', 'journal-title': 'Br. J. Herpet.'} / Br. J. Herpet. / The skin of snakes and lizards by Maderson P. F. A. (1964)
Maderson P. F. A.1967The histology of the escutcheon scales ofGonatodes(Gekkonidae) with a comment on the squamate sloughing cycle.Copeia:743–752. (10.2307/1441884)
{'key': 'e_1_2_1_8_1', 'first-page': '1146', 'article-title': 'The regeneration of epidermal specializations on lizard caudal scales', 'volume': '9', 'author': 'Maderson P. F. A.', 'year': '1969', 'journal-title': 'Am. Zool.'} / Am. Zool. / The regeneration of epidermal specializations on lizard caudal scales by Maderson P. F. A. (1969)
{'key': 'e_1_2_1_9_1', 'first-page': '179', 'article-title': 'Lizard glands and lizard hands: models for evolutionary study', 'volume': '3', 'author': 'Maderson P. F. A.', 'year': '1970', 'journal-title': 'Forma et Functio'} / Forma et Functio / Lizard glands and lizard hands: models for evolutionary study by Maderson P. F. A. (1970)
10.1002/jmor.1051340407
{'key': 'e_1_2_1_11_1', 'first-page': '259', 'article-title': 'Endocrine‐epidermal relationships in squamate reptiles', 'volume': '18', 'author': 'Maderson P. F. A.', 'year': '1970', 'journal-title': 'Mem. Soc. Endocrinol.'} / Mem. Soc. Endocrinol. / Endocrine‐epidermal relationships in squamate reptiles by Maderson P. F. A. (1970)
Maderson P. F. A. B. A. Flaxman S. I.RothandG.Szabo1972Ultrastructural contributions to the identification of cell types in the lizard epidermis.J. Morph. in press. (10.1002/jmor.1051360205)
10.1002/jmor.1051230205
{'key': 'e_1_2_1_14_1', 'first-page': '556', 'article-title': 'Observations on integumentary regeneration in lizards', 'volume': '10', 'author': 'Maderson P. F. A.', 'year': '1970', 'journal-title': 'Am. Zool.'} / Am. Zool. / Observations on integumentary regeneration in lizards by Maderson P. F. A. (1970)
{'key': 'e_1_2_1_15_1', 'series-title': 'Advances in the Biology of Skin', 'first-page': '254', 'volume-title': 'Wound Healing', 'author': 'Montagna W.', 'year': '1964'} / Wound Healing / Advances in the Biology of Skin by Montagna W. (1964)
{'key': 'e_1_2_1_16_1', 'first-page': '420', 'volume-title': 'Cellular Biology of Vertebrate Regeneration and Repair', 'author': 'Schmidt A. J.', 'year': '1968'} / Cellular Biology of Vertebrate Regeneration and Repair by Schmidt A. J. (1968)

Dates

Type	When
Created	20 years, 2 months ago (June 12, 2005, 1:03 a.m.)
Deposited	1 year, 9 months ago (Nov. 12, 2023, 5:36 a.m.)
Indexed	2 months, 3 weeks ago (June 11, 2025, 5:03 p.m.)
Issued	53 years, 4 months ago (May 1, 1972)
Published	53 years, 4 months ago (May 1, 1972)
Published Online	20 years, 3 months ago (May 10, 2005)
Published Print	53 years, 4 months ago (May 1, 1972)

Funders 0

None

BibTeX

@article{Maderson_1972, title={A histological study of the early stages of cutaneous wound healing in lizards in in vivo and in vitro}, volume={180}, ISSN={1097-010X}, url={http://dx.doi.org/10.1002/jez.1401800205}, DOI={10.1002/jez.1401800205}, number={2}, journal={Journal of Experimental Zoology}, publisher={Wiley}, author={Maderson, P. F. A. and Roth, S. I.}, year={1972}, month=may, pages={175–185} }

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