Gastrulation in the mouse embryo: Ultrastructural and molecular aspects of germ layer morphogenesis
10.1002/jemt.1070260405
Crossref journal-article
Wiley
Microscopy Research and Technique (311)
Abstract

AbstractUltrastructural studies and lineage analyses of gastrulating mouse embryos have revealed that differnt morphogenetic tissue movements are involved in the formation of the three definitive germ layers. Definitive ectoderm is formed by epibolic expansion of the pre‐existing progenitor population in the embryonic ectoderm. Formation of the mesoderm and the endoderm is initiated by cellular ingression at the primitive streak. The mesodermal layer is established by cell migration and cell sheet spreading, but the endoderm is formed by replacing the original primitive endodermal population. To this date, genes that are expressed during mouse gastrulation mostly encode cell surface adhesion or signalling molecules, growth factors and their receptors, and putative transcriptional factors. Their precise role during gastrulation remains to be investigated. © 1993 Wiley‐Liss, Inc.

Bibliography

Tam, P. P. L., Williams, E. A., & Chan, W. Y. (1993). Gastrulation in the mouse embryo: Ultrastructural and molecular aspects of germ layer morphogenesis. Microscopy Research and Technique, 26(4), 301–328. Portico.

Authors 3
  1. Patrick P. L. Tam (first)
  2. Elizabeth A. Williams (additional)
  3. W. Y. Chan (additional)
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Dates
Type When
Created 20 years, 6 months ago (Feb. 23, 2005, 5:23 p.m.)
Deposited 8 months, 1 week ago (Dec. 23, 2024, 10:47 a.m.)
Indexed 5 months, 1 week ago (March 22, 2025, 4:48 a.m.)
Issued 31 years, 10 months ago (Nov. 1, 1993)
Published 31 years, 10 months ago (Nov. 1, 1993)
Published Online 20 years, 6 months ago (Feb. 4, 2005)
Published Print 31 years, 10 months ago (Nov. 1, 1993)
Funders 0

None

@article{Tam_1993, title={Gastrulation in the mouse embryo: Ultrastructural and molecular aspects of germ layer morphogenesis}, volume={26}, ISSN={1097-0029}, url={http://dx.doi.org/10.1002/jemt.1070260405}, DOI={10.1002/jemt.1070260405}, number={4}, journal={Microscopy Research and Technique}, publisher={Wiley}, author={Tam, Patrick P. L. and Williams, Elizabeth A. and Chan, W. Y.}, year={1993}, month=nov, pages={301–328} }