DOI: 10.1002/jcp.1040760113. Studies on colony formation <i>in vitro</i> by mouse bone marrow cells. II. Action of colony stimulating factor

Studies on colony formation in vitro by mouse bone marrow cells. II. Action of colony stimulating factor

10.1002/jcp.1040760113

Crossref journal-article

Wiley

Journal of Cellular Physiology (311)

Abstract

AbstractAn analysis was made of some of the processes involved in the stimulation by colony stimulating factor (CSF) of cluster and colony formation by mouse bone marrow cells in agar cultures in vitro. Colony formation was shown to be related to the concentration and not the total amount of CSF. The concentration of CSF determined the rate of new cluster initiation in cultures and the rate of growth of individual clusters. Colony growth depleted the medium of CSF suggesting that colony cells may utilise CSF during proliferation. Bone marrow cells incubated in agar in the absence of CSF rapidly died or lost their capacity to proliferate and form clusters or colonies. CSF appears (a) to be necessary for survival of cluster‐and colony‐forming cells or for survival of their proliferative potential, (b) to shorten the lag period before individual cells commence proliferation and (c) to increase the growth rate of individual clusters and colonies.

Bibliography

Metcalf, D. (1970). Studies on colony formation in vitro by mouse bone marrow cells. II. Action of colony stimulating factor. Journal of Cellular Physiology, 76(1), 89â99. Portico.

Authors 1

Donald Metcalf (first)

References 13 Referenced 151

10.1038/icb.1966.28
{'key': 'e_1_2_1_3_1', 'first-page': '22', 'volume-title': 'Hemic Cells In Vitro 4', 'author': 'Bradley T. R.', 'year': '1969'} / Hemic Cells In Vitro 4 by Bradley T. R. (1969)
10.1038/icb.1968.167
10.1111/j.1365-2141.1968.tb01524.x
10.1002/jcp.1040720104
10.1002/jcp.1040740313
10.1002/jcp.1040690112
{'key': 'e_1_2_1_9_1', 'first-page': '1235', 'article-title': 'Bone marrow colony stimulating activity of serum from mice with viral‐induced leukemia', 'volume': '39', 'author': 'Metcalf D.', 'year': '1967', 'journal-title': 'J. Natl. Canc. Instit.'} / J. Natl. Canc. Instit. / Bone marrow colony stimulating activity of serum from mice with viral‐induced leukemia by Metcalf D. (1967)
10.3181/00379727-126-32563
10.1038/icb.1969.50
10.1002/jcp.1040690111
10.1038/icb.1969.51
{'key': 'e_1_2_1_14_1', 'first-page': '1118', 'article-title': 'The control of cell division: A review. II. Special mechanisms', 'volume': '18', 'author': 'Swann M. M.', 'year': '1958', 'journal-title': 'Cancer Research'} / Cancer Research / The control of cell division: A review. II. Special mechanisms by Swann M. M. (1958)

Dates

Type	When
Created	20 years, 6 months ago (Feb. 25, 2005, 10:30 p.m.)
Deposited	1 year, 9 months ago (Nov. 11, 2023, 11:43 p.m.)
Indexed	11 months, 3 weeks ago (Sept. 5, 2024, 12:42 p.m.)
Issued	55 years ago (Aug. 1, 1970)
Published	55 years ago (Aug. 1, 1970)
Published Online	20 years, 6 months ago (Feb. 4, 2005)
Published Print	55 years ago (Aug. 1, 1970)

Funders 0

None

BibTeX

@article{Metcalf_1970, title={Studies on colony formation in vitro by mouse bone marrow cells. II. Action of colony stimulating factor}, volume={76}, ISSN={1097-4652}, url={http://dx.doi.org/10.1002/jcp.1040760113}, DOI={10.1002/jcp.1040760113}, number={1}, journal={Journal of Cellular Physiology}, publisher={Wiley}, author={Metcalf, Donald}, year={1970}, month=aug, pages={89–99} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2024,
        9,
        5
      ]
    ],
    "date-time": "2024-09-05T16:42:17Z",
    "timestamp": 1725554537084
  },
  "reference-count": 13,
  "publisher": "Wiley",
  "issue": "1",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2005,
            2,
            4
          ]
        ],
        "date-time": "2005-02-04T00:00:00Z",
        "timestamp": 1107475200000
      },
      "content-version": "vor",
      "delay-in-days": 12606,
      "URL": "http://onlinelibrary.wiley.com/termsAndConditions#vor"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1970,
        8
      ]
    ]
  },
  "abstract": "<jats:title>Abstract</jats:title><jats:p>An analysis was made of some of the processes involved in the stimulation by colony stimulating factor (CSF) of cluster and colony formation by mouse bone marrow cells in agar cultures <jats:italic>in vitro</jats:italic>. Colony formation was shown to be related to the concentration and not the total amount of CSF. The concentration of CSF determined the rate of new cluster initiation in cultures and the rate of growth of individual clusters. Colony growth depleted the medium of CSF suggesting that colony cells may utilise CSF during proliferation. Bone marrow cells incubated in agar in the absence of CSF rapidly died or lost their capacity to proliferate and form clusters or colonies. CSF appears (a) to be necessary for survival of cluster\u2010and colony\u2010forming cells or for survival of their proliferative potential, (b) to shorten the lag period before individual cells commence proliferation and (c) to increase the growth rate of individual clusters and colonies.</jats:p>",
  "DOI": "10.1002/jcp.1040760113",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2005,
        2,
        26
      ]
    ],
    "date-time": "2005-02-26T03:30:09Z",
    "timestamp": 1109388609000
  },
  "page": "89-99",
  "source": "Crossref",
  "is-referenced-by-count": 151,
  "title": "Studies on colony formation <i>in vitro</i> by mouse bone marrow cells. II. Action of colony stimulating factor",
  "prefix": "10.1002",
  "volume": "76",
  "author": [
    {
      "given": "Donald",
      "family": "Metcalf",
      "sequence": "first",
      "affiliation": []
    }
  ],
  "member": "311",
  "published-online": {
    "date-parts": [
      [
        2005,
        2,
        4
      ]
    ]
  },
  "reference": [
    {
      "key": "e_1_2_1_2_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/icb.1966.28"
    },
    {
      "key": "e_1_2_1_3_1",
      "first-page": "22",
      "volume-title": "Hemic Cells In Vitro 4",
      "author": "Bradley T. R.",
      "year": "1969"
    },
    {
      "key": "e_1_2_1_4_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/icb.1968.167"
    },
    {
      "key": "e_1_2_1_5_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1111/j.1365-2141.1968.tb01524.x"
    },
    {
      "key": "e_1_2_1_6_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/jcp.1040720104"
    },
    {
      "key": "e_1_2_1_7_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/jcp.1040740313"
    },
    {
      "key": "e_1_2_1_8_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/jcp.1040690112"
    },
    {
      "key": "e_1_2_1_9_1",
      "first-page": "1235",
      "article-title": "Bone marrow colony stimulating activity of serum from mice with viral\u2010induced leukemia",
      "volume": "39",
      "author": "Metcalf D.",
      "year": "1967",
      "journal-title": "J. Natl. Canc. Instit."
    },
    {
      "key": "e_1_2_1_10_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.3181/00379727-126-32563"
    },
    {
      "key": "e_1_2_1_11_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/icb.1969.50"
    },
    {
      "key": "e_1_2_1_12_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/jcp.1040690111"
    },
    {
      "key": "e_1_2_1_13_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/icb.1969.51"
    },
    {
      "key": "e_1_2_1_14_1",
      "first-page": "1118",
      "article-title": "The control of cell division: A review. II. Special mechanisms",
      "volume": "18",
      "author": "Swann M. M.",
      "year": "1958",
      "journal-title": "Cancer Research"
    }
  ],
  "container-title": "Journal of Cellular Physiology",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fjcp.1040760113",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcp.1040760113",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        11,
        12
      ]
    ],
    "date-time": "2023-11-12T04:43:21Z",
    "timestamp": 1699764201000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://onlinelibrary.wiley.com/doi/10.1002/jcp.1040760113"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1970,
        8
      ]
    ]
  },
  "references-count": 13,
  "journal-issue": {
    "issue": "1",
    "published-print": {
      "date-parts": [
        [
          1970,
          8
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1002/jcp.1040760113"
  ],
  "URL": "http://dx.doi.org/10.1002/jcp.1040760113",
  "relation": {},
  "ISSN": [
    "0021-9541",
    "1097-4652"
  ],
  "subject": [],
  "container-title-short": "Journal Cellular Physiology",
  "published": {
    "date-parts": [
      [
        1970,
        8
      ]
    ]
  }
}