DOI: 10.1002/jbmr.5650100406. Solar ultraviolet B radiation and photoproduction of vitamin D3 in central and southern areas of argentina

Solar ultraviolet B radiation and photoproduction of vitamin D3 in central and southern areas of argentina

10.1002/jbmr.5650100406

Crossref journal-article

Oxford University Press (OUP)

Journal of Bone and Mineral Research (286)

Abstract

Abstract The incidence of nutritional rickets in the southern part of Argentina is 8–12 times higher than in the rest of the country. Winter 25(OH)D serum levels in normal population of southern areas are lower than in central and northern areas. To elucidate these differences, we compared the photoconversion of provitamin D3 (7-DHC) to previtamin D3 in two cities: Ushuaia (latitude 55°S) and Buenos Aires (34°S). Ampules containing 7-DHC were exposed to sunlight one day in the middle of each month either from 10:30 a.m. to 2:30 p.m. or from 8:00 a.m. to 5:00 p.m. The percentages of photoproducts formed were determined by high performance liquid chromatography (HPLC). Previous studies have proved that this is a valid model to assess “in vitro” the photoproduction of vitamin D3 in human skin. Previtamin D3 + vitamin D3 formed in Ushuaia were less (p &lt; 0.02) than those found in Buenos Aires during all seasons: summer, (X ± SEM) 6.4 ± 0.8% vs. 13.2 ± 1.8%; autumn, 1.2 ± 0.7% vs. 63 ± 1.3%; winter, 0.8 ± 0.7% vs. 3.6 ± 0.7%; spring, 3.4 ± 0.5% vs. 9.1 ± 1.1%. The photoproducts produced from 10:30 a.m. to 2:30 p.m. were similar for each month and latitude to those formed when the ampules were exposed from 8:00 a.m. to 5:00 p.m. We conclude that in Ushuaia there is a prolonged “vitamin D winter” during which cutaneous synthesis of vitamin D is absent, leading to lower serum values of 25(OH)D and contributing to the higher incidence of rickets.

Bibliography

Ladizesky, M., Lu, Z., Oliveri, B., Roman, N. S., Diaz, S., Holick, M. F., & Mautalen, C. (1995). Solar ultraviolet B radiation and photoproduction of vitamin D3 in central and southern areas of argentina. Journal of Bone and Mineral Research, 10(4), 545â549.

Authors 7

Marta Ladizesky (first)
Zhiren Lu (additional)
Beatriz Oliveri (additional)
Nemesio San Roman (additional)
Susana Diaz (additional)
Michael F. Holick (additional)
Carlos Mautalen (additional)

References 29 Referenced 79

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Dates

Type	When
Created	15 years, 7 months ago (Feb. 3, 2010, 11:07 a.m.)
Deposited	1 year, 5 months ago (March 13, 2024, 11 a.m.)
Indexed	11 months, 3 weeks ago (Sept. 10, 2024, 7:50 p.m.)
Issued	30 years, 5 months ago (April 1, 1995)
Published	30 years, 5 months ago (April 1, 1995)
Published Online	30 years, 5 months ago (April 1, 1995)
Published Print	30 years, 5 months ago (April 1, 1995)

Funders 0

None

BibTeX

@article{Ladizesky_1995, title={Solar ultraviolet B radiation and photoproduction of vitamin D3 in central and southern areas of argentina}, volume={10}, ISSN={1523-4681}, url={http://dx.doi.org/10.1002/jbmr.5650100406}, DOI={10.1002/jbmr.5650100406}, number={4}, journal={Journal of Bone and Mineral Research}, publisher={Oxford University Press (OUP)}, author={Ladizesky, Marta and Lu, Zhiren and Oliveri, Beatriz and Roman, Nemesio San and Diaz, Susana and Holick, Michael F. and Mautalen, Carlos}, year={1995}, month=apr, pages={545–549} }

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  "abstract": "<jats:title>Abstract</jats:title>\n               <jats:p>The incidence of nutritional rickets in the southern part of Argentina is 8\u201312 times higher than in the rest of the country. Winter 25(OH)D serum levels in normal population of southern areas are lower than in central and northern areas. To elucidate these differences, we compared the photoconversion of provitamin D3 (7-DHC) to previtamin D3 in two cities: Ushuaia (latitude 55\u00b0S) and Buenos Aires (34\u00b0S). Ampules containing 7-DHC were exposed to sunlight one day in the middle of each month either from 10:30 a.m. to 2:30 p.m. or from 8:00 a.m. to 5:00 p.m. The percentages of photoproducts formed were determined by high performance liquid chromatography (HPLC). Previous studies have proved that this is a valid model to assess \u201cin vitro\u201d the photoproduction of vitamin D3 in human skin. Previtamin D3 + vitamin D3 formed in Ushuaia were less (p &amp;lt; 0.02) than those found in Buenos Aires during all seasons: summer, (X \u00b1 SEM) 6.4 \u00b1 0.8% vs. 13.2 \u00b1 1.8%; autumn, 1.2 \u00b1 0.7% vs. 63 \u00b1 1.3%; winter, 0.8 \u00b1 0.7% vs. 3.6 \u00b1 0.7%; spring, 3.4 \u00b1 0.5% vs. 9.1 \u00b1 1.1%. The photoproducts produced from 10:30 a.m. to 2:30 p.m. were similar for each month and latitude to those formed when the ampules were exposed from 8:00 a.m. to 5:00 p.m. We conclude that in Ushuaia there is a prolonged \u201cvitamin D winter\u201d during which cutaneous synthesis of vitamin D is absent, leading to lower serum values of 25(OH)D and contributing to the higher incidence of rickets.</jats:p>",
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      "volume": "216",
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      "volume": "67",
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