DOI: 10.1002/ijc.2910380205. Risk of colorectal cancer in adenoma‐bearing individuals within a defined population

Risk of colorectal cancer in adenoma‐bearing individuals within a defined population

10.1002/ijc.2910380205

Crossref journal-article

Wiley

International Journal of Cancer (311)

Abstract

AbstractAssuming that all colorectal cancers develop from preexisting adenomas, the annual conversion rate, defined as the number of cancers occurring each year as a percentage of all adenoma‐bearing individuals, was determined. The number of adenoma‐bearing individuals in the living population of northern Norway was estimated in each cohort for the period 1974–76 by determining the prevalence of colorectal adenomas in an autopsy population of 271 consecutive cases, representative of the population of the area with regard to underlying causes of death. During the 10‐year period 1974–1983 a total of 656 colorectal cancers were recorded among an estimated number of 26,419 adenoma‐bearing individuals aged over 35 years. The annual conversion rate was found to be 0.25%, indicating that an average adenoma‐bearing individual is only at a moderate risk of colorectal cancer. The annual conversion rates for individuals having large adenomas, or adenomas with villous structures, or severe dyspla‐ sia were roughly estimated to be 3%, 17% and 37% respectively, assuming that colorectal cancer develops from one of these sub‐groups of adenomas only.

Bibliography

Eide, T. J. (1986). Risk of colorectal cancer in adenomaâbearing individuals within a defined population. International Journal of Cancer, 38(2), 173â176. Portico.

Authors 1

Tor J. Eide (first)

References 16 Referenced 175

{'key': 'e_1_2_1_2_1', 'volume-title': 'Population by age and marital status', 'author': 'CENTRAL BUREAU OF STATISTICS, NORWAY', 'year': '1976'} / Population by age and marital status by CENTRAL BUREAU OF STATISTICS, NORWAY (1976)
{'key': 'e_1_2_1_3_1', 'volume-title': 'Mortality in counties 1969–1972', 'author': 'CENTRAL BUREAU OF STATISTICS, NORWAY', 'year': '1974'} / Mortality in counties 1969–1972 by CENTRAL BUREAU OF STATISTICS, NORWAY (1974)
10.1002/ijc.2910360209
10.1002/1097-0142(19830515)51:10<1866::AID-CNCR2820511019>3.0.CO;2-X
Eide T. J. Prevalence and morphological features of adenomas of the large intestine in individuals with and without colorectal carcinoma.Histopathology.In press. (1986). (10.1111/j.1365-2559.1986.tb02467.x)
10.1002/1097-0142(197812)42:6<2839::AID-CNCR2820420645>3.0.CO;2-Y
10.1097/00000658-197510000-00017
10.3109/00365528309181847
{'key': 'e_1_2_1_10_1', 'first-page': '158', 'article-title': 'Adenomas and carcinomas of the large bowel. Distinct diseases possibly sharing common etiologic factors?', 'volume': '45', 'author': 'Maskens A. D.', 'year': '1982', 'journal-title': 'Acta gastro‐enterol. belg.'} / Acta gastro‐enterol. belg. / Adenomas and carcinomas of the large bowel. Distinct diseases possibly sharing common etiologic factors? by Maskens A. D. (1982)
{'key': 'e_1_2_1_11_1', 'volume-title': 'Histological typing of intestinal tumours', 'author': 'Morson B. C.', 'year': '1976'} / Histological typing of intestinal tumours by Morson B. C. (1976)
10.1002/cncr.2820360944
10.1002/1097-0142(19850401)55:7<1586::AID-CNCR2820550729>3.0.CO;2-I
10.1097/00000658-197912000-00001
10.1016/S0025-6196(12)61425-6
10.1002/1097-0142(19820215)49:4<819::AID-CNCR2820490435>3.0.CO;2-D
10.1136/gut.23.10.835

Dates

Type	When
Created	18 years, 6 months ago (Feb. 19, 2007, 3:18 p.m.)
Deposited	1 year, 10 months ago (Oct. 20, 2023, 6:29 p.m.)
Indexed	2 weeks, 2 days ago (Aug. 22, 2025, 12:47 a.m.)
Issued	39 years ago (Aug. 15, 1986)
Published	39 years ago (Aug. 15, 1986)
Published Online	19 years, 1 month ago (July 17, 2006)
Published Print	39 years ago (Aug. 15, 1986)

Funders 0

None

BibTeX

@article{Eide_1986, title={Risk of colorectal cancer in adenoma‐bearing individuals within a defined population}, volume={38}, ISSN={1097-0215}, url={http://dx.doi.org/10.1002/ijc.2910380205}, DOI={10.1002/ijc.2910380205}, number={2}, journal={International Journal of Cancer}, publisher={Wiley}, author={Eide, Tor J.}, year={1986}, month=aug, pages={173–176} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        22
      ]
    ],
    "date-time": "2025-08-22T04:47:41Z",
    "timestamp": 1755838061204
  },
  "reference-count": 16,
  "publisher": "Wiley",
  "issue": "2",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2006,
            7,
            17
          ]
        ],
        "date-time": "2006-07-17T00:00:00Z",
        "timestamp": 1153094400000
      },
      "content-version": "vor",
      "delay-in-days": 7276,
      "URL": "http://onlinelibrary.wiley.com/termsAndConditions#vor"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1986,
        8,
        15
      ]
    ]
  },
  "abstract": "<jats:title>Abstract</jats:title><jats:p>Assuming that all colorectal cancers develop from preexisting adenomas, the annual conversion rate, defined as the number of cancers occurring each year as a percentage of all adenoma\u2010bearing individuals, was determined. The number of adenoma\u2010bearing individuals in the living population of northern Norway was estimated in each cohort for the period 1974\u201376 by determining the prevalence of colorectal adenomas in an autopsy population of 271 consecutive cases, representative of the population of the area with regard to underlying causes of death. During the 10\u2010year period 1974\u20131983 a total of 656 colorectal cancers were recorded among an estimated number of 26,419 adenoma\u2010bearing individuals aged over 35 years. The annual conversion rate was found to be 0.25%, indicating that an average adenoma\u2010bearing individual is only at a moderate risk of colorectal cancer. The annual conversion rates for individuals having large adenomas, or adenomas with villous structures, or severe dyspla\u2010 sia were roughly estimated to be 3%, 17% and 37% respectively, assuming that colorectal cancer develops from one of these sub\u2010groups of adenomas only.</jats:p>",
  "DOI": "10.1002/ijc.2910380205",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2007,
        2,
        19
      ]
    ],
    "date-time": "2007-02-19T20:18:30Z",
    "timestamp": 1171916310000
  },
  "page": "173-176",
  "source": "Crossref",
  "is-referenced-by-count": 175,
  "title": "Risk of colorectal cancer in adenoma\u2010bearing individuals within a defined population",
  "prefix": "10.1002",
  "volume": "38",
  "author": [
    {
      "given": "Tor J.",
      "family": "Eide",
      "sequence": "first",
      "affiliation": []
    }
  ],
  "member": "311",
  "published-online": {
    "date-parts": [
      [
        2006,
        7,
        17
      ]
    ]
  },
  "reference": [
    {
      "key": "e_1_2_1_2_1",
      "volume-title": "Population by age and marital status",
      "author": "CENTRAL BUREAU OF STATISTICS, NORWAY",
      "year": "1976"
    },
    {
      "key": "e_1_2_1_3_1",
      "volume-title": "Mortality in counties 1969\u20131972",
      "author": "CENTRAL BUREAU OF STATISTICS, NORWAY",
      "year": "1974"
    },
    {
      "key": "e_1_2_1_4_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/ijc.2910360209"
    },
    {
      "key": "e_1_2_1_5_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/1097-0142(19830515)51:10<1866::AID-CNCR2820511019>3.0.CO;2-X"
    },
    {
      "key": "e_1_2_1_6_1",
      "doi-asserted-by": "crossref",
      "unstructured": "Eide T. J. Prevalence and morphological features of adenomas of the large intestine in individuals with and without colorectal carcinoma.Histopathology.In press. (1986).",
      "DOI": "10.1111/j.1365-2559.1986.tb02467.x"
    },
    {
      "key": "e_1_2_1_7_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/1097-0142(197812)42:6<2839::AID-CNCR2820420645>3.0.CO;2-Y"
    },
    {
      "key": "e_1_2_1_8_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1097/00000658-197510000-00017"
    },
    {
      "key": "e_1_2_1_9_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.3109/00365528309181847"
    },
    {
      "key": "e_1_2_1_10_1",
      "first-page": "158",
      "article-title": "Adenomas and carcinomas of the large bowel. Distinct diseases possibly sharing common etiologic factors?",
      "volume": "45",
      "author": "Maskens A. D.",
      "year": "1982",
      "journal-title": "Acta gastro\u2010enterol. belg."
    },
    {
      "key": "e_1_2_1_11_1",
      "volume-title": "Histological typing of intestinal tumours",
      "author": "Morson B. C.",
      "year": "1976"
    },
    {
      "key": "e_1_2_1_12_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/cncr.2820360944"
    },
    {
      "key": "e_1_2_1_13_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/1097-0142(19850401)55:7<1586::AID-CNCR2820550729>3.0.CO;2-I"
    },
    {
      "key": "e_1_2_1_14_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1097/00000658-197912000-00001"
    },
    {
      "key": "e_1_2_1_15_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0025-6196(12)61425-6"
    },
    {
      "key": "e_1_2_1_16_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/1097-0142(19820215)49:4<819::AID-CNCR2820490435>3.0.CO;2-D"
    },
    {
      "key": "e_1_2_1_17_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1136/gut.23.10.835"
    }
  ],
  "container-title": "International Journal of Cancer",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fijc.2910380205",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://onlinelibrary.wiley.com/doi/pdf/10.1002/ijc.2910380205",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        10,
        20
      ]
    ],
    "date-time": "2023-10-20T22:29:50Z",
    "timestamp": 1697840990000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://onlinelibrary.wiley.com/doi/10.1002/ijc.2910380205"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1986,
        8,
        15
      ]
    ]
  },
  "references-count": 16,
  "journal-issue": {
    "issue": "2",
    "published-print": {
      "date-parts": [
        [
          1986,
          8,
          15
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1002/ijc.2910380205"
  ],
  "URL": "http://dx.doi.org/10.1002/ijc.2910380205",
  "relation": {},
  "ISSN": [
    "0020-7136",
    "1097-0215"
  ],
  "subject": [],
  "container-title-short": "Intl Journal of Cancer",
  "published": {
    "date-parts": [
      [
        1986,
        8,
        15
      ]
    ]
  }
}