DOI: 10.1002/ijc.2910210207. Two E‐rosette‐forming lymphoid cell lines

Two E‐rosette‐forming lymphoid cell lines

10.1002/ijc.2910210207

Crossref journal-article

Wiley

International Journal of Cancer (311)

Abstract

AbstractTwo E‐rosette (spontaneous rosette with sheep red blood cells)‐forming lymphoid cell lines were established. One (HPB‐ALL) was derived from a young male Japanese patient with acute lympho‐blastic leukemia (ALL), and the other (HPB‐MLT) was from a 62‐year‐old female Japanese patient with a leukemic T‐lymphoid malignancy. Formation of E rosettes, absence of any immunoglobulin determinants, absence of EBNA (Epstein‐Barr virus associated nuclear antigen) and very limited stimulating ability in mixed lymphocyte culture, were characteristics mostly identical with those of so far established T‐cell‐derived lymphoid cell lines, MOLT, CCRF‐CEM, CCRF‐HS‐B2, RPMI‐8402 and JM. Only HPB‐MLT, however, has been derived from an aged patient with T‐lymphoid malignancy.

Bibliography

Morikawa, S., Tatsumi, E., Baba, M., Harada, T., & Yasuhira, K. (1978). Two Eârosetteâforming lymphoid cell lines. International Journal of Cancer, 21(2), 166â170. Portico.

Authors 5

Shigeru Morikawa (first)
Eiji Tatsumi (additional)
Mitsuo Baba (additional)
Takayuki Harada (additional)
Kimio Yasuhira (additional)

References 37 Referenced 116

{'key': 'e_1_2_1_2_1', 'first-page': '1121', 'article-title': 'Direct implantation and serial transplantation of human acute lymphoblastic leukemia in hamsters, SB‐2', 'volume': '28', 'author': 'Adams R. A.', 'year': '1968', 'journal-title': 'Cancer Res.'} / Cancer Res. / Direct implantation and serial transplantation of human acute lymphoblastic leukemia in hamsters, SB‐2 by Adams R. A. (1968)
{'issue': '97', 'key': 'e_1_2_1_3_1', 'first-page': '77', 'article-title': 'Separation of leucocytes from blood and bone marrow', 'volume': '21', 'author': 'Böyum A.', 'year': '1968', 'journal-title': 'Scand. J. clin. lab. Invest.'} / Scand. J. clin. lab. Invest. / Separation of leucocytes from blood and bone marrow by Böyum A. (1968)
10.1016/S0140-6736(75)92127-3
10.1016/0008-8749(75)90209-9
10.1016/S0140-6736(73)93135-8
10.4049/jimmunol.113.4.1122 / J. Immunol. / Immunologic functions of isolated human lymphocyte subpopulation. II. Antigen triggering of T and B cells in vitro by Chess L. (1974)
10.1038/257147a0
10.1073/pnas.73.1.228
10.1002/1097-0142(196504)18:4<522::AID-CNCR2820180418>3.0.CO;2-J
10.1111/j.1365-2141.1974.tb06769.x
{'key': 'e_1_2_1_12_1', 'first-page': '535', 'article-title': 'A unique “leukemic” T lymphoid cell line: absence of stimulating effect in mixed lymphocyte reaction', 'volume': '15', 'author': 'Han T.', 'year': '1973', 'journal-title': 'Clin. exp. Immunol.'} / Clin. exp. Immunol. / A unique “leukemic” T lymphoid cell line: absence of stimulating effect in mixed lymphocyte reaction by Han T. (1973)
10.1038/252602a0
{'key': 'e_1_2_1_14_1', 'first-page': '367', 'article-title': 'Surface receptors on human hematopoietic cell lines', 'volume': '25', 'author': 'Huber C. H.', 'year': '1976', 'journal-title': 'Clin. exp. Immunol.'} / Clin. exp. Immunol. / Surface receptors on human hematopoietic cell lines by Huber C. H. (1976)
10.1084/jem.136.2.207
10.1002/ijc.2910190412
10.1084/jem.139.5.1070
10.1073/pnas.71.8.3283
10.1038/230531a0
10.1038/250144a0
10.1126/science.183.4126.757
10.7326/0003-4819-83-4-534
{'key': 'e_1_2_1_23_1', 'first-page': '251', 'volume-title': 'Comparative leukemia research', 'author': 'Minowada J.', 'year': '1975'} / Comparative leukemia research by Minowada J. (1975)
{'key': 'e_1_2_1_24_1', 'first-page': '891', 'article-title': 'Rosetteforming human lymphoid cell lines. I. Establishment and evidence for origin of thymus‐derived lymphocytes', 'volume': '49', 'author': 'Minowada J.', 'year': '1972', 'journal-title': 'J. nat. Cancer Inst.'} / J. nat. Cancer Inst. / Rosetteforming human lymphoid cell lines. I. Establishment and evidence for origin of thymus‐derived lymphocytes by Minowada J. (1972)
10.1002/ijc.2910080311
10.1002/ijc.2910150217
{'key': 'e_1_2_1_27_1', 'first-page': '557', 'article-title': 'Disparity of mixed lymphocyte reactivity to cultured cells of human T and B lymphoid lines', 'volume': '54', 'author': 'Pauly J. L.', 'year': '1975', 'journal-title': 'J. nat. Cancer Inst.'} / J. nat. Cancer Inst. / Disparity of mixed lymphocyte reactivity to cultured cells of human T and B lymphoid lines by Pauly J. L. (1975)
10.1056/NEJM197301252880403
10.1038/newbio245247a0
10.1002/ijc.2910110302
10.1093/jnci/53.2.361 / J. nat. Cancer Inst. / Failure of cultured human T‐cell lymphoid lines to stimulate in mixed leucocyte culture by Royston I. (1974)
10.1038/251745a0
10.1002/ijc.2910190505
10.1002/eji.1830050706
{'key': 'e_1_2_1_35_1', 'first-page': '276', 'article-title': 'Immunologic functions of isolated human lymphocyte subpopulations. 4. Stimulation of MLC and CML by human T cells', 'volume': '19', 'author': 'Sondel P. M.', 'year': '1975', 'journal-title': 'Cell. Immunol.'} / Cell. Immunol. / Immunologic functions of isolated human lymphocyte subpopulations. 4. Stimulation of MLC and CML by human T cells by Sondel P. M. (1975)
10.1016/S0140-6736(73)92040-0
10.1016/0008-8749(74)90178-6
10.1056/NEJM197403072901019

Dates

Type	When
Created	18 years, 6 months ago (Feb. 19, 2007, 12:03 p.m.)
Deposited	1 year, 9 months ago (Nov. 12, 2023, 12:10 a.m.)
Indexed	1 week, 2 days ago (Aug. 21, 2025, 12:29 p.m.)
Issued	47 years, 6 months ago (Feb. 15, 1978)
Published	47 years, 6 months ago (Feb. 15, 1978)
Published Online	19 years, 1 month ago (July 17, 2006)
Published Print	47 years, 6 months ago (Feb. 15, 1978)

Funders 0

None

BibTeX

@article{Morikawa_1978, title={Two E‐rosette‐forming lymphoid cell lines}, volume={21}, ISSN={1097-0215}, url={http://dx.doi.org/10.1002/ijc.2910210207}, DOI={10.1002/ijc.2910210207}, number={2}, journal={International Journal of Cancer}, publisher={Wiley}, author={Morikawa, Shigeru and Tatsumi, Eiji and Baba, Mitsuo and Harada, Takayuki and Yasuhira, Kimio}, year={1978}, month=feb, pages={166–170} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        21
      ]
    ],
    "date-time": "2025-08-21T16:29:39Z",
    "timestamp": 1755793779787
  },
  "reference-count": 37,
  "publisher": "Wiley",
  "issue": "2",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2006,
            7,
            17
          ]
        ],
        "date-time": "2006-07-17T00:00:00Z",
        "timestamp": 1153094400000
      },
      "content-version": "vor",
      "delay-in-days": 10379,
      "URL": "http://onlinelibrary.wiley.com/termsAndConditions#vor"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1978,
        2,
        15
      ]
    ]
  },
  "abstract": "<jats:title>Abstract</jats:title><jats:p>Two E\u2010rosette (spontaneous rosette with sheep red blood cells)\u2010forming lymphoid cell lines were established. One (HPB\u2010ALL) was derived from a young male Japanese patient with acute lympho\u2010blastic leukemia (ALL), and the other (HPB\u2010MLT) was from a 62\u2010year\u2010old female Japanese patient with a leukemic T\u2010lymphoid malignancy. Formation of E rosettes, absence of any immunoglobulin determinants, absence of EBNA (Epstein\u2010Barr virus associated nuclear antigen) and very limited stimulating ability in mixed lymphocyte culture, were characteristics mostly identical with those of so far established T\u2010cell\u2010derived lymphoid cell lines, MOLT, CCRF\u2010CEM, CCRF\u2010HS\u2010B2, RPMI\u20108402 and JM. Only HPB\u2010MLT, however, has been derived from an aged patient with T\u2010lymphoid malignancy.</jats:p>",
  "DOI": "10.1002/ijc.2910210207",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2007,
        2,
        19
      ]
    ],
    "date-time": "2007-02-19T17:03:41Z",
    "timestamp": 1171904621000
  },
  "page": "166-170",
  "source": "Crossref",
  "is-referenced-by-count": 116,
  "title": "Two E\u2010rosette\u2010forming lymphoid cell lines",
  "prefix": "10.1002",
  "volume": "21",
  "author": [
    {
      "given": "Shigeru",
      "family": "Morikawa",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Eiji",
      "family": "Tatsumi",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Mitsuo",
      "family": "Baba",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Takayuki",
      "family": "Harada",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Kimio",
      "family": "Yasuhira",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "311",
  "published-online": {
    "date-parts": [
      [
        2006,
        7,
        17
      ]
    ]
  },
  "reference": [
    {
      "key": "e_1_2_1_2_1",
      "first-page": "1121",
      "article-title": "Direct implantation and serial transplantation of human acute lymphoblastic leukemia in hamsters, SB\u20102",
      "volume": "28",
      "author": "Adams R. A.",
      "year": "1968",
      "journal-title": "Cancer Res."
    },
    {
      "issue": "97",
      "key": "e_1_2_1_3_1",
      "first-page": "77",
      "article-title": "Separation of leucocytes from blood and bone marrow",
      "volume": "21",
      "author": "B\u00f6yum A.",
      "year": "1968",
      "journal-title": "Scand. J. clin. lab. Invest."
    },
    {
      "key": "e_1_2_1_4_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0140-6736(75)92127-3"
    },
    {
      "key": "e_1_2_1_5_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0008-8749(75)90209-9"
    },
    {
      "key": "e_1_2_1_6_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0140-6736(73)93135-8"
    },
    {
      "key": "e_1_2_1_7_1",
      "doi-asserted-by": "crossref",
      "first-page": "1122",
      "DOI": "10.4049/jimmunol.113.4.1122",
      "article-title": "Immunologic functions of isolated human lymphocyte subpopulation. II. Antigen triggering of T and B cells in vitro",
      "volume": "113",
      "author": "Chess L.",
      "year": "1974",
      "journal-title": "J. Immunol."
    },
    {
      "key": "e_1_2_1_8_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/257147a0"
    },
    {
      "key": "e_1_2_1_9_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.73.1.228"
    },
    {
      "key": "e_1_2_1_10_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/1097-0142(196504)18:4<522::AID-CNCR2820180418>3.0.CO;2-J"
    },
    {
      "key": "e_1_2_1_11_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1111/j.1365-2141.1974.tb06769.x"
    },
    {
      "key": "e_1_2_1_12_1",
      "first-page": "535",
      "article-title": "A unique \u201cleukemic\u201d T lymphoid cell line: absence of stimulating effect in mixed lymphocyte reaction",
      "volume": "15",
      "author": "Han T.",
      "year": "1973",
      "journal-title": "Clin. exp. Immunol."
    },
    {
      "key": "e_1_2_1_13_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/252602a0"
    },
    {
      "key": "e_1_2_1_14_1",
      "first-page": "367",
      "article-title": "Surface receptors on human hematopoietic cell lines",
      "volume": "25",
      "author": "Huber C. H.",
      "year": "1976",
      "journal-title": "Clin. exp. Immunol."
    },
    {
      "key": "e_1_2_1_15_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1084/jem.136.2.207"
    },
    {
      "key": "e_1_2_1_16_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/ijc.2910190412"
    },
    {
      "key": "e_1_2_1_17_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1084/jem.139.5.1070"
    },
    {
      "key": "e_1_2_1_18_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.71.8.3283"
    },
    {
      "key": "e_1_2_1_19_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/230531a0"
    },
    {
      "key": "e_1_2_1_20_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/250144a0"
    },
    {
      "key": "e_1_2_1_21_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.183.4126.757"
    },
    {
      "key": "e_1_2_1_22_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.7326/0003-4819-83-4-534"
    },
    {
      "key": "e_1_2_1_23_1",
      "first-page": "251",
      "volume-title": "Comparative leukemia research",
      "author": "Minowada J.",
      "year": "1975"
    },
    {
      "key": "e_1_2_1_24_1",
      "first-page": "891",
      "article-title": "Rosetteforming human lymphoid cell lines. I. Establishment and evidence for origin of thymus\u2010derived lymphocytes",
      "volume": "49",
      "author": "Minowada J.",
      "year": "1972",
      "journal-title": "J. nat. Cancer Inst."
    },
    {
      "key": "e_1_2_1_25_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/ijc.2910080311"
    },
    {
      "key": "e_1_2_1_26_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/ijc.2910150217"
    },
    {
      "key": "e_1_2_1_27_1",
      "first-page": "557",
      "article-title": "Disparity of mixed lymphocyte reactivity to cultured cells of human T and B lymphoid lines",
      "volume": "54",
      "author": "Pauly J. L.",
      "year": "1975",
      "journal-title": "J. nat. Cancer Inst."
    },
    {
      "key": "e_1_2_1_28_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1056/NEJM197301252880403"
    },
    {
      "key": "e_1_2_1_29_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/newbio245247a0"
    },
    {
      "key": "e_1_2_1_30_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/ijc.2910110302"
    },
    {
      "key": "e_1_2_1_31_1",
      "doi-asserted-by": "crossref",
      "first-page": "361",
      "DOI": "10.1093/jnci/53.2.361",
      "article-title": "Failure of cultured human T\u2010cell lymphoid lines to stimulate in mixed leucocyte culture",
      "volume": "63",
      "author": "Royston I.",
      "year": "1974",
      "journal-title": "J. nat. Cancer Inst."
    },
    {
      "key": "e_1_2_1_32_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/251745a0"
    },
    {
      "key": "e_1_2_1_33_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/ijc.2910190505"
    },
    {
      "key": "e_1_2_1_34_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/eji.1830050706"
    },
    {
      "key": "e_1_2_1_35_1",
      "first-page": "276",
      "article-title": "Immunologic functions of isolated human lymphocyte subpopulations. 4. Stimulation of MLC and CML by human T cells",
      "volume": "19",
      "author": "Sondel P. M.",
      "year": "1975",
      "journal-title": "Cell. Immunol."
    },
    {
      "key": "e_1_2_1_36_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0140-6736(73)92040-0"
    },
    {
      "key": "e_1_2_1_37_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0008-8749(74)90178-6"
    },
    {
      "key": "e_1_2_1_38_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1056/NEJM197403072901019"
    }
  ],
  "container-title": "International Journal of Cancer",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fijc.2910210207",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://onlinelibrary.wiley.com/doi/pdf/10.1002/ijc.2910210207",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        11,
        12
      ]
    ],
    "date-time": "2023-11-12T05:10:59Z",
    "timestamp": 1699765859000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://onlinelibrary.wiley.com/doi/10.1002/ijc.2910210207"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1978,
        2,
        15
      ]
    ]
  },
  "references-count": 37,
  "journal-issue": {
    "issue": "2",
    "published-print": {
      "date-parts": [
        [
          1978,
          2,
          15
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1002/ijc.2910210207"
  ],
  "URL": "http://dx.doi.org/10.1002/ijc.2910210207",
  "relation": {},
  "ISSN": [
    "0020-7136",
    "1097-0215"
  ],
  "subject": [],
  "container-title-short": "Intl Journal of Cancer",
  "published": {
    "date-parts": [
      [
        1978,
        2,
        15
      ]
    ]
  }
}