DOI: 10.1002/ijc.2910200511. Characterization of immunoglobulins in Hodgkin cells

Characterization of immunoglobulins in Hodgkin cells

10.1002/ijc.2910200511

Crossref journal-article

Wiley

International Journal of Cancer (311)

Abstract

AbstractFifteen of 42 formalin‐fixed lymph‐node biopsies with Hodgkin lesions of different histological types and stages gave positive staining for immunoglobulins by the peroxidase/antiperoxidase method. The immunoglobulins in all the positively stained Hodgkin cells were of IgG type, but staining for IgA, D and E was negative. One of the 15 biopsies was positive for IgM. Thirteen of the 15 positive biopsies were positive for both χ and λ. Sequential double staining using two different substrates for peroxidase showed that most of the Hodgkin cells simultaneously contained light chains of both χ and λ type. It is concluded that Hodgkin cells do not contain a “monoclonal” immunoglobulin product.

Bibliography

Landaas, T. Ã¸., Godal, T., & Halvorsen, T. B. (1977). Characterization of immunoglobulins in Hodgkin cells. International Journal of Cancer, 20(5), 717â722. Portico.

Authors 3

Tone ø. Landaas (first)
Tore Godal (additional)
Tore B. Halvorsen (additional)

References 28 Referenced 42

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Dates

Type	When
Created	18 years, 6 months ago (Feb. 19, 2007, 12:04 p.m.)
Deposited	1 year, 9 months ago (Nov. 12, 2023, 11 a.m.)
Indexed	1 year, 7 months ago (Jan. 21, 2024, 10:31 a.m.)
Issued	47 years, 9 months ago (Nov. 15, 1977)
Published	47 years, 9 months ago (Nov. 15, 1977)
Published Online	19 years, 1 month ago (July 17, 2006)
Published Print	47 years, 9 months ago (Nov. 15, 1977)

Funders 0

None

BibTeX

@article{Landaas_1977, title={Characterization of immunoglobulins in Hodgkin cells}, volume={20}, ISSN={1097-0215}, url={http://dx.doi.org/10.1002/ijc.2910200511}, DOI={10.1002/ijc.2910200511}, number={5}, journal={International Journal of Cancer}, publisher={Wiley}, author={Landaas, Tone ø. and Godal, Tore and Halvorsen, Tore B.}, year={1977}, month=nov, pages={717–722} }

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