DOI: 10.1002/ijc.2910040209. Decreased interferon sensitivity and production in cells transformed by sv40 and other oncogenic agents

Decreased interferon sensitivity and production in cells transformed by sv40 and other oncogenic agents

10.1002/ijc.2910040209

Crossref journal-article

Wiley

International Journal of Cancer (311)

Abstract

AbstractFrom a pool of primary rat embryo fibroblast cells, three lines—two SV40‐infected and one control—were serially propagated. Prior to unequivocal morphological evidence of transformation, increased sensitivity to vesicular stomatitis virus (VSV) was found in the two SV40‐infected lines when compared to the control line. The increased VSV sensitivity of the transformed cells seems to be due to a diminished production of and sensitivity to interferon, and not to differences in adsorption. When a collection of diverse transformed cell lines were also compared with arbitrarily selected control cell populations, the majority of the transformed cells also exhibited enhanced VSV sensitivity. Lines transformed by methylcholanthrene also featured this property. The data suggest that diminished sensitivity to and production of interferon is an early consequence of infection by oncogenic viruses, and a property that persists in many lines of transformed cells.

Bibliography

Brailovsky, C. A., Berman, L. D., & Chany, C. H. (1969). Decreased interferon sensitivity and production in cells transformed by sv40 and other oncogenic agents. International Journal of Cancer, 4(2), 194â203. Portico.

Authors 3

C. A. Brailovsky (first)
L. D. Berman (additional)
C. H. Chany (additional)

References 39 Referenced 16

10.1016/0042-6822(61)90075-7
{'key': 'e_1_2_1_3_1', 'first-page': '462', 'volume-title': 'Viruses, nucleic acids, and cancer', 'author': 'Allison A. C.', 'year': '1963'} / Viruses, nucleic acids, and cancer by Allison A. C. (1963)
{'key': 'e_1_2_1_4_1', 'first-page': '1687', 'article-title': "Action d'un interféron provenant de cellules malignes sur l'infection expérimentale du hamster nouveau‐né par le virus du polyoma", 'volume': '251', 'author': 'Atanasiu P.', 'year': '1960', 'journal-title': 'C. R. Acad. Sci. (Paris)'} / C. R. Acad. Sci. (Paris) / Action d'un interféron provenant de cellules malignes sur l'infection expérimentale du hamster nouveau‐né par le virus du polyoma by Atanasiu P. (1960)
{'key': 'e_1_2_1_5_1', 'first-page': '447', 'article-title': 'Infection virale inapparente de cellules de hamsters décelée par la microscopie électronique', 'volume': '107', 'author': 'Bernhard W.', 'year': '1964', 'journal-title': 'Ann. Inst. Pasteur'} / Ann. Inst. Pasteur / Infection virale inapparente de cellules de hamsters décelée par la microscopie électronique by Bernhard W. (1964)
Berman L. D. andChany C. Inhibition and stimulation in acute nonlytic infections of adenovirus and SV 40. In preparation (1969).
Brailovsky C. andBerman L. D. Unpublished observations (1968).
{'key': 'e_1_2_1_8_1', 'first-page': '2133', 'article-title': "Extraction de stimulon de cellules transformées par l'adénovirus 12 ou par le virus simien 40 (SV 40)", 'volume': '266', 'author': 'Brailovsky C.', 'year': '1968', 'journal-title': 'C. R. Acad. Sci. (Paris)'} / C. R. Acad. Sci. (Paris) / Extraction de stimulon de cellules transformées par l'adénovirus 12 ou par le virus simien 40 (SV 40) by Brailovsky C. (1968)
10.1073/pnas.57.1.87
{'key': 'e_1_2_1_10_1', 'first-page': '1339', 'article-title': "Interaction stimulante entre le virus du sarcome murin (VMS) et le virus de l'hépatite murine (VHM)", 'volume': '266', 'author': 'Chany C.', 'year': '1968', 'journal-title': 'C. R. Acad. Sci. (Paris)'} / C. R. Acad. Sci. (Paris) / Interaction stimulante entre le virus du sarcome murin (VMS) et le virus de l'hépatite murine (VHM) by Chany C. (1968)
10.1016/0042-6822(67)90160-2
10.3181/00379727-124-31963
10.1007/BF01258475
10.1007/BF01257732
10.3181/00379727-92-22627
10.3181/00379727-112-28040
10.1016/0042-6822(63)90072-2
{'key': 'e_1_2_1_18_1', 'first-page': '99', 'article-title': 'Production and susceptibility to interferon of polyoma virus variants of high and low oncogenic properties', 'volume': '37', 'author': 'Gotlieb‐Stematsky T.', 'year': '1966', 'journal-title': 'J. nat. Cancer Inst.'} / J. nat. Cancer Inst. / Production and susceptibility to interferon of polyoma virus variants of high and low oncogenic properties by Gotlieb‐Stematsky T. (1966)
{'key': 'e_1_2_1_19_1', 'first-page': '291', 'article-title': "Présence de particules d'aspect viral dans un sarcome greffable de la souris provoqué par le méthylcholanthrène", 'volume': '47', 'author': 'Granboulan N.', 'year': '1960', 'journal-title': 'Bull. Ass. franç. Cancer'} / Bull. Ass. franç. Cancer / Présence de particules d'aspect viral dans un sarcome greffable de la souris provoqué par le méthylcholanthrène by Granboulan N. (1960)
10.3181/00379727-124-31673
{'key': 'e_1_2_1_21_1', 'first-page': '3541', 'article-title': "Présence de particules d'aspect viral dans les thymomes transplantables des souris DBA/2. Etude ultramorphologique de leur formation", 'volume': '256', 'author': 'Haguenau F.', 'year': '1963', 'journal-title': 'C. R. Acad. Sci. (Paris)'} / C. R. Acad. Sci. (Paris) / Présence de particules d'aspect viral dans les thymomes transplantables des souris DBA/2. Etude ultramorphologique de leur formation by Haguenau F. (1963)
10.1126/science.156.3771.85
{'key': 'e_1_2_1_23_1', 'first-page': '1511', 'article-title': 'Resistance levels of polyoma tumors and tumors of other origin to the cytopathogenic effect of polyoma virus', 'volume': '31', 'author': 'HellströM I.', 'year': '1963', 'journal-title': 'J. nat. Cancer Inst.'} / J. nat. Cancer Inst. / Resistance levels of polyoma tumors and tumors of other origin to the cytopathogenic effect of polyoma virus by HellströM I. (1963)
{'key': 'e_1_2_1_24_1', 'first-page': '209', 'article-title': 'Sensitivity of mouse tumor cells to the antiviral action of interferon', 'volume': '33', 'author': 'HellströM I.', 'year': '1964', 'journal-title': 'J. nat. Cancer Inst.'} / J. nat. Cancer Inst. / Sensitivity of mouse tumor cells to the antiviral action of interferon by HellströM I. (1964)
10.1016/0014-4827(62)90171-4
{'key': 'e_1_2_1_26_1', 'first-page': '1525', 'article-title': 'Correlation between the sensitivity of polyoma‐induced mouse tumors to polyoma and vaccinia virus in vitro', 'volume': '31', 'author': 'HellströM I.', 'year': '1963', 'journal-title': 'J. nat. Cancer Inst.'} / J. nat. Cancer Inst. / Correlation between the sensitivity of polyoma‐induced mouse tumors to polyoma and vaccinia virus in vitro by HellströM I. (1963)
10.1016/0042-6822(62)90249-0
{'key': 'e_1_2_1_28_1', 'first-page': '143', 'article-title': 'Differences in response of hamster tumor cells induced by polyoma virus to interfering virus and interferon', 'volume': '31', 'author': 'Henle G.', 'year': '1963', 'journal-title': 'J. nat. Cancer Inst.'} / J. nat. Cancer Inst. / Differences in response of hamster tumor cells induced by polyoma virus to interfering virus and interferon by Henle G. (1963)
10.1038/1811213b0
10.1007/BF01240510
10.1016/0042-6822(68)90255-9
10.1016/0042-6822(66)90248-0
Rubin H. InThe Williams and Wilkins Company Baltimore (ed.)Viruses nucleic acids and cancer 484(1963).
10.1002/ijc.2910020304
10.1016/0042-6822(67)90111-0
10.3181/00379727-122-31365
10.1016/0042-6822(66)90249-2
10.1002/ijc.2910020207
10.3181/00379727-122-31289
Wicker R. Berman L. D. Suarez H. Tournier P. andBrailovsky C. Studies on the transformation of rat cells by SV40. In preparation (1969).

Dates

Type	When
Created	18 years, 6 months ago (Feb. 19, 2007, 7:45 a.m.)
Deposited	1 year, 9 months ago (Nov. 12, 2023, 2:14 a.m.)
Indexed	1 year, 9 months ago (Nov. 12, 2023, 7:11 p.m.)
Issued	56 years, 5 months ago (March 15, 1969)
Published	56 years, 5 months ago (March 15, 1969)
Published Online	19 years, 1 month ago (July 18, 2006)
Published Print	56 years, 5 months ago (March 15, 1969)

Funders 0

None

BibTeX

@article{Brailovsky_1969, title={Decreased interferon sensitivity and production in cells transformed by sv40 and other oncogenic agents}, volume={4}, ISSN={1097-0215}, url={http://dx.doi.org/10.1002/ijc.2910040209}, DOI={10.1002/ijc.2910040209}, number={2}, journal={International Journal of Cancer}, publisher={Wiley}, author={Brailovsky, C. A. and Berman, L. D. and Chany, C. H.}, year={1969}, month=mar, pages={194–203} }

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