DOI: 10.1002/hep.1840050427. The Liver Sieve: Considerations Concerning the Structure and Function of Endothelial Fenestrae, the Sinusoidal Wall and the Space of Disse

The Liver Sieve: Considerations Concerning the Structure and Function of Endothelial Fenestrae, the Sinusoidal Wall and the Space of Disse

10.1002/hep.1840050427

Crossref journal-article

Ovid Technologies (Wolters Kluwer Health)

Hepatology (276)

Bibliography

Wisse, E., de Zanger, R. B., Charels, K., van der Smissen, P., & McCuskey, R. S. (1985). The Liver Sieve: Considerations Concerning the Structure and Function of Endothelial Fenestrae, the Sinusoidal Wall and the Space of Disse. Hepatology, 5(4), 683â692.

Authors 5

E. Wisse (first)
R. B. de Zanger (additional)
K. Charels (additional)
P. van der Smissen (additional)
R. S. McCuskey (additional)

References 49 Referenced 590

10.1016/S0022-5320(70)90150-4 / J Ultrastruct Res by Wisse (1970)
10.1016/0022-5320(72)90089-5 / J Ultrastruct Res by Wisse (1972)
{'key': '10.1002/hep.1840050427-BIB3', 'first-page': '119', 'volume': '6', 'author': 'Ito', 'year': '1973', 'journal-title': 'Gunma Rep Med Sci'} / Gunma Rep Med Sci by Ito (1973)
. The investigation of sinusoidal cells: a new approach to the study of liver function. In: , eds. Progress in liver diseases, Vol VI. New York: Grune and Stratton, 1979: 153–171. / Progress in liver diseases by Wisse (1979)
, . Perfusion fixation of human and rat liver tissue for light and electron microscopy: a review and assessment of existing methods with special emphasis on sinusoidal cells and microcirculation. Science of Biological Specimen Preparation, Chicago: SEM Inc AMF O'Hare, 1984: 31–38. / Science of Biological Specimen Preparation by Wisse (1984)
. The filtration effect of rat liver fenestrated sinusoidal endothelium on the passage of (remnant) chylomicrons to the space of Disse. In: , eds. Sinusoidal liver cells. Amsterdam: Elsevier, 1982: 69–76. / Sinusoidal liver cells by De Zanger (1982)
{'key': '10.1002/hep.1840050427-BIB7', 'first-page': '71', 'volume': '23', 'author': 'Sandström', 'year': '1970', 'journal-title': 'Lab Invest'} / Lab Invest by Sandström (1970)
10.1679/aohc1950.40.137 / Arch Histol Japan by Muto (1977)
, , et al. On the fixation of needle biopsies of rat liver tissue as a model to study the fine structure of sinusoidal cells. In: , eds. Sinusoidal liver cells. Amsterdam: Elsevier, 1982: 85–92. / Sinusoidal liver cells by De Wilde (1982)
10.1002/ar.1091900407 / Anat Rec by Montesano (1978)
{'key': '10.1002/hep.1840050427-BIB11', 'first-page': '60', 'volume': '29', 'author': 'Brooks', 'year': '1973', 'journal-title': 'Lab Invest'} / Lab Invest by Brooks (1973)
10.1679/aohc1950.37.15 / Arch Histol Jap by Itoshima (1974)
10.1007/BF00224322 / Cell Tiss Res by Motta (1974)
, , et al. Scanning electron microscope observations on the structure of portal veins, sinusoids and central veins in rat liver. Scanning electron microscopy III. SEM, Inc. AMF O'Hare, Chicago, Illinois. 1983: 1441–1452. / Scanning electron microscopy III by Wisse (1983)
10.1007/BF00219553 / Cell Tissue Res by Naito (1978)
10.1016/0021-9150(78)90001-1 / Atherosclerosis by Fraser (1978)
{'key': '10.1002/hep.1840050427-BIB17', 'first-page': '344', 'volume': '3', 'author': 'Wright', 'year': '1983', 'journal-title': 'Atherosclerosis'} / Atherosclerosis by Wright (1983)
10.3109/00313028009077098 / Pathology by Fraser (1980)
10.1002/hep.1840040306 / Hepatology by Mak (1984)
10.1083/jcb.64.2.356 / J Cell Biol by Glaumann (1975)
10.1002/aja.1001590102 / Amer J Anat by Bankston (1980)
10.1002/ar.1091700106 / Anat Rec by Grubb (1971)
10.1038/icb.1983.69 / Aust J Exp Biol Med Sci by Wright (1983)
10.1002/ar.1092060405 / Anat Rec by Wright (1983)
10.1002/ar.1091720106 / Anat Rec by Gemmell (1972)
, , et al. On the distribution of collagen, fibronectin and laminin in the normal rat liver. In: , eds. Sinusoidal liver cells. Amsterdam: Elsevier, 1982: 209–217. / Sinusoidal liver cells by Geerts (1982)
{'key': '10.1002/hep.1840050427-BIB27', 'first-page': '476', 'volume': '12', 'author': 'Okazaki', 'year': '1973', 'journal-title': 'Bibl Anat'} / Bibl Anat by Okazaki (1973)
10.1002/sca.4950010206 / Scanning by Murakami (1978)
, , et al. Agents related to fibrosis, such as alcohol and CCI4 acutely affect endothelial fenestrae which may cause fatty liver. In: et al., eds. Connective tissue of the normal and fibrotic human liver. Stuttgart: Thième Verlag, 1982: 159–160. / Connective tissue of the normal and fibrotic human liver by Fraser (1982)
{'key': '10.1002/hep.1840050427-BIB30', 'first-page': '222', 'volume': '61', 'author': 'Fraser', 'year': '1980', 'journal-title': 'Br J Exp Pathol'} / Br J Exp Pathol by Fraser (1980)
10.1007/BF01851321 / Res Exp Med by Frenzel (1976)
{'key': '10.1002/hep.1840050427-BIB32', 'first-page': '604', 'volume': '57', 'author': 'Nopanitaya', 'year': '1976', 'journal-title': 'Br J Exp Pathol'} / Br J Exp Pathol by Nopanitaya (1976)
, . The liver sinusoids under various pathological conditions. A TEM and SEM study of rat liver after respiratory hypoxia, telecobalt-irradiation and endotoxin application. In: , eds. Kupffer cells and other liver sinusoidal cells. Amsterdam: Elsevier, 1977: 213–222. / Kupffer cells and other liver sinusoidal cells by Frenzel (1977)
, . et al. On the role of the liver endothelial filter in the transport of particulate fat (chylomicrons and their remnants) to parenchymal cells and the influence of certain hormones on endothelial fenestrae. In: Proc Basler Liver Week 1979. London, England: MTP Press, 1980: 195–200. / Proc Basler Liver Week 1979 by Wisse (1980)
, , et al. Some dynamic aspects of the hepatic microcirculation–Demonstration of sinusoidal endothelial fenestrae as a possible regulatory factor. In: et al., eds. Intravital observation of organ microcirculation. The Hague: Excerpta Medica Foundation, 1983: 105–138. / Intravital observation of organ microcirculation by Oda (1983)
{'key': '10.1002/hep.1840050427-BIB36', 'first-page': '5', 'volume': '16', 'author': 'Oda', 'year': '1983', 'journal-title': 'J Clin Electr Microsc'} / J Clin Electr Microsc by Oda (1983)
10.1083/jcb.37.3.633 / J Cell Biol by Palade (1968)
{'key': '10.1002/hep.1840050427-BIB38', 'first-page': '79', 'volume': '37', 'author': 'Ogawa', 'year': '1983', 'journal-title': 'Acta Med Okayama'} / Acta Med Okayama by Ogawa (1983)
10.1016/0014-4827(77)90011-8 / Exp Cell Res by Knook (1977)
10.1016/0014-4827(76)90605-4 / Exp Cell Res by Knook (1976)
{'key': '10.1002/hep.1840050427-BIB41', 'first-page': '809', 'volume': '292', 'author': 'Steffan', 'year': '1981', 'journal-title': 'Comp Rend Acad Sci Paris'} / Comp Rend Acad Sci Paris by Steffan (1981)
10.1007/BF00221510 / Cell Tissue Res by De Leeuw (1982)
. Liver cell heterogeneity. In: et al., eds. The liver: biology and pathobiology. New York: Raven Press, 1982: 647. / The liver: biology and pathobiology by Gumucio (1982)
10.1002/aja.1001190307 / Amer J Anat by McCuskey (1966)
{'key': '10.1002/hep.1840050427-BIB45', 'first-page': '73', 'volume': '18', 'author': 'McCuskey', 'year': '1979', 'journal-title': 'Biblio Anat'} / Biblio Anat by McCuskey (1979)
{'key': '10.1002/hep.1840050427-BIB46', 'first-page': '79', 'volume': '59', 'author': 'McCuskey', 'year': '1981', 'journal-title': 'Prog Clin Biol Res'} / Prog Clin Biol Res by McCuskey (1981)
The hepatic microvascular system. In: , , eds. Microcirculation of the alimentary tract–Physiology and pathophysiology. Singapore: World Science Publishing Co., 1983: 57–58. / Microcirculation of the alimentary tract–Physiology and pathophysiology by McCuskey (1983)
10.1002/aja.1001190107 / Amer J Anat by Heath (1966)
10.1113/expphysiol.1975.sp002320 / J Exp Physiol by Koo (1975)

Dates

Type	When
Created	18 years, 5 months ago (March 3, 2007, 2:21 p.m.)
Deposited	8 months, 3 weeks ago (Dec. 1, 2024, 6:11 a.m.)
Indexed	1 day, 10 hours ago (Aug. 24, 2025, 6:51 p.m.)
Issued	40 years, 1 month ago (July 1, 1985)
Published	40 years, 1 month ago (July 1, 1985)
Published Print	40 years, 1 month ago (July 1, 1985)

Funders 0

None

BibTeX

@article{Wisse_1985, title={The Liver Sieve: Considerations Concerning the Structure and Function of Endothelial Fenestrae, the Sinusoidal Wall and the Space of Disse}, volume={5}, ISSN={0270-9139}, url={http://dx.doi.org/10.1002/hep.1840050427}, DOI={10.1002/hep.1840050427}, number={4}, journal={Hepatology}, publisher={Ovid Technologies (Wolters Kluwer Health)}, author={Wisse, E. and de Zanger, R. B. and Charels, K. and van der Smissen, P. and McCuskey, R. S.}, year={1985}, month=jul, pages={683–692} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        24
      ]
    ],
    "date-time": "2025-08-24T22:51:01Z",
    "timestamp": 1756075861276,
    "version": "3.30.0"
  },
  "reference-count": 49,
  "publisher": "Ovid Technologies (Wolters Kluwer Health)",
  "issue": "4",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2015,
            9,
            1
          ]
        ],
        "date-time": "2015-09-01T00:00:00Z",
        "timestamp": 1441065600000
      },
      "content-version": "tdm",
      "delay-in-days": 11019,
      "URL": "http://doi.wiley.com/10.1002/tdm_license_1.1"
    }
  ],
  "content-domain": {
    "domain": [
      "lww.com",
      "ovid.com"
    ],
    "crossmark-restriction": true
  },
  "published-print": {
    "date-parts": [
      [
        1985,
        7
      ]
    ]
  },
  "DOI": "10.1002/hep.1840050427",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2007,
        3,
        3
      ]
    ],
    "date-time": "2007-03-03T19:21:40Z",
    "timestamp": 1172949700000
  },
  "page": "683-692",
  "update-policy": "http://dx.doi.org/10.1097/lww.0000000000001000",
  "source": "Crossref",
  "is-referenced-by-count": 590,
  "title": "The Liver Sieve: Considerations Concerning the Structure and Function of Endothelial Fenestrae, the Sinusoidal Wall and the Space of Disse",
  "prefix": "10.1097",
  "volume": "5",
  "author": [
    {
      "given": "E.",
      "family": "Wisse",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "R. B.",
      "family": "de Zanger",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "K.",
      "family": "Charels",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "P.",
      "family": "van der Smissen",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "R. S.",
      "family": "McCuskey",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "276",
  "reference": [
    {
      "key": "10.1002/hep.1840050427-BIB1",
      "doi-asserted-by": "crossref",
      "first-page": "125",
      "DOI": "10.1016/S0022-5320(70)90150-4",
      "volume": "31",
      "author": "Wisse",
      "year": "1970",
      "journal-title": "J Ultrastruct Res"
    },
    {
      "key": "10.1002/hep.1840050427-BIB2",
      "doi-asserted-by": "crossref",
      "first-page": "528",
      "DOI": "10.1016/0022-5320(72)90089-5",
      "volume": "38",
      "author": "Wisse",
      "year": "1972",
      "journal-title": "J Ultrastruct Res"
    },
    {
      "key": "10.1002/hep.1840050427-BIB3",
      "first-page": "119",
      "volume": "6",
      "author": "Ito",
      "year": "1973",
      "journal-title": "Gunma Rep Med Sci"
    },
    {
      "key": "10.1002/hep.1840050427-BIB4",
      "first-page": "153",
      "volume-title": "Progress in liver diseases",
      "author": "Wisse",
      "year": "1979",
      "unstructured": ". The investigation of sinusoidal cells: a new approach to the study of liver function. In: , eds. Progress in liver diseases, Vol VI. New York: Grune and Stratton, 1979: 153\u2013171."
    },
    {
      "key": "10.1002/hep.1840050427-BIB5",
      "first-page": "31",
      "volume-title": "Science of Biological Specimen Preparation",
      "author": "Wisse",
      "year": "1984",
      "unstructured": ", . Perfusion fixation of human and rat liver tissue for light and electron microscopy: a review and assessment of existing methods with special emphasis on sinusoidal cells and microcirculation. Science of Biological Specimen Preparation, Chicago: SEM Inc AMF O'Hare, 1984: 31\u201338."
    },
    {
      "key": "10.1002/hep.1840050427-BIB6",
      "first-page": "69",
      "volume-title": "Sinusoidal liver cells",
      "author": "De Zanger",
      "year": "1982",
      "unstructured": ". The filtration effect of rat liver fenestrated sinusoidal endothelium on the passage of (remnant) chylomicrons to the space of Disse. In: , eds. Sinusoidal liver cells. Amsterdam: Elsevier, 1982: 69\u201376."
    },
    {
      "key": "10.1002/hep.1840050427-BIB7",
      "first-page": "71",
      "volume": "23",
      "author": "Sandstr\u00f6m",
      "year": "1970",
      "journal-title": "Lab Invest"
    },
    {
      "key": "10.1002/hep.1840050427-BIB8",
      "doi-asserted-by": "crossref",
      "first-page": "137",
      "DOI": "10.1679/aohc1950.40.137",
      "volume": "40",
      "author": "Muto",
      "year": "1977",
      "journal-title": "Arch Histol Japan"
    },
    {
      "key": "10.1002/hep.1840050427-BIB9",
      "first-page": "85",
      "volume-title": "Sinusoidal liver cells",
      "author": "De Wilde",
      "year": "1982",
      "unstructured": ", , et al. On the fixation of needle biopsies of rat liver tissue as a model to study the fine structure of sinusoidal cells. In: , eds. Sinusoidal liver cells. Amsterdam: Elsevier, 1982: 85\u201392."
    },
    {
      "key": "10.1002/hep.1840050427-BIB10",
      "doi-asserted-by": "crossref",
      "first-page": "861",
      "DOI": "10.1002/ar.1091900407",
      "volume": "190",
      "author": "Montesano",
      "year": "1978",
      "journal-title": "Anat Rec"
    },
    {
      "key": "10.1002/hep.1840050427-BIB11",
      "first-page": "60",
      "volume": "29",
      "author": "Brooks",
      "year": "1973",
      "journal-title": "Lab Invest"
    },
    {
      "key": "10.1002/hep.1840050427-BIB12",
      "doi-asserted-by": "crossref",
      "first-page": "15",
      "DOI": "10.1679/aohc1950.37.15",
      "volume": "37",
      "author": "Itoshima",
      "year": "1974",
      "journal-title": "Arch Histol Jap"
    },
    {
      "key": "10.1002/hep.1840050427-BIB13",
      "doi-asserted-by": "crossref",
      "first-page": "111",
      "DOI": "10.1007/BF00224322",
      "volume": "148",
      "author": "Motta",
      "year": "1974",
      "journal-title": "Cell Tiss Res"
    },
    {
      "key": "10.1002/hep.1840050427-BIB14",
      "first-page": "1441",
      "volume-title": "Scanning electron microscopy III",
      "author": "Wisse",
      "year": "1983",
      "unstructured": ", , et al. Scanning electron microscope observations on the structure of portal veins, sinusoids and central veins in rat liver. Scanning electron microscopy III. SEM, Inc. AMF O'Hare, Chicago, Illinois. 1983: 1441\u20131452."
    },
    {
      "key": "10.1002/hep.1840050427-BIB15",
      "doi-asserted-by": "crossref",
      "first-page": "371",
      "DOI": "10.1007/BF00219553",
      "volume": "190",
      "author": "Naito",
      "year": "1978",
      "journal-title": "Cell Tissue Res"
    },
    {
      "key": "10.1002/hep.1840050427-BIB16",
      "doi-asserted-by": "crossref",
      "first-page": "113",
      "DOI": "10.1016/0021-9150(78)90001-1",
      "volume": "29",
      "author": "Fraser",
      "year": "1978",
      "journal-title": "Atherosclerosis"
    },
    {
      "key": "10.1002/hep.1840050427-BIB17",
      "first-page": "344",
      "volume": "3",
      "author": "Wright",
      "year": "1983",
      "journal-title": "Atherosclerosis"
    },
    {
      "key": "10.1002/hep.1840050427-BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "371",
      "DOI": "10.3109/00313028009077098",
      "volume": "12",
      "author": "Fraser",
      "year": "1980",
      "journal-title": "Pathology"
    },
    {
      "key": "10.1002/hep.1840050427-BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "386",
      "DOI": "10.1002/hep.1840040306",
      "volume": "4",
      "author": "Mak",
      "year": "1984",
      "journal-title": "Hepatology"
    },
    {
      "key": "10.1002/hep.1840050427-BIB20",
      "doi-asserted-by": "crossref",
      "first-page": "356",
      "DOI": "10.1083/jcb.64.2.356",
      "volume": "64",
      "author": "Glaumann",
      "year": "1975",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "10.1002/hep.1840050427-BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "1",
      "DOI": "10.1002/aja.1001590102",
      "volume": "159",
      "author": "Bankston",
      "year": "1980",
      "journal-title": "Amer J Anat"
    },
    {
      "key": "10.1002/hep.1840050427-BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "75",
      "DOI": "10.1002/ar.1091700106",
      "volume": "170",
      "author": "Grubb",
      "year": "1971",
      "journal-title": "Anat Rec"
    },
    {
      "key": "10.1002/hep.1840050427-BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "739",
      "DOI": "10.1038/icb.1983.69",
      "volume": "61",
      "author": "Wright",
      "year": "1983",
      "journal-title": "Aust J Exp Biol Med Sci"
    },
    {
      "key": "10.1002/hep.1840050427-BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "385",
      "DOI": "10.1002/ar.1092060405",
      "volume": "206",
      "author": "Wright",
      "year": "1983",
      "journal-title": "Anat Rec"
    },
    {
      "key": "10.1002/hep.1840050427-BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "57",
      "DOI": "10.1002/ar.1091720106",
      "volume": "172",
      "author": "Gemmell",
      "year": "1972",
      "journal-title": "Anat Rec"
    },
    {
      "key": "10.1002/hep.1840050427-BIB26",
      "first-page": "209",
      "volume-title": "Sinusoidal liver cells",
      "author": "Geerts",
      "year": "1982",
      "unstructured": ", , et al. On the distribution of collagen, fibronectin and laminin in the normal rat liver. In: , eds. Sinusoidal liver cells. Amsterdam: Elsevier, 1982: 209\u2013217."
    },
    {
      "key": "10.1002/hep.1840050427-BIB27",
      "first-page": "476",
      "volume": "12",
      "author": "Okazaki",
      "year": "1973",
      "journal-title": "Bibl Anat"
    },
    {
      "key": "10.1002/hep.1840050427-BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "127",
      "DOI": "10.1002/sca.4950010206",
      "volume": "1",
      "author": "Murakami",
      "year": "1978",
      "journal-title": "Scanning"
    },
    {
      "key": "10.1002/hep.1840050427-BIB29",
      "first-page": "159",
      "volume-title": "Connective tissue of the normal and fibrotic human liver",
      "author": "Fraser",
      "year": "1982",
      "unstructured": ", , et al. Agents related to fibrosis, such as alcohol and CCI4 acutely affect endothelial fenestrae which may cause fatty liver. In: et al., eds. Connective tissue of the normal and fibrotic human liver. Stuttgart: Thi\u00e8me Verlag, 1982: 159\u2013160."
    },
    {
      "key": "10.1002/hep.1840050427-BIB30",
      "first-page": "222",
      "volume": "61",
      "author": "Fraser",
      "year": "1980",
      "journal-title": "Br J Exp Pathol"
    },
    {
      "key": "10.1002/hep.1840050427-BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "229",
      "DOI": "10.1007/BF01851321",
      "volume": "168",
      "author": "Frenzel",
      "year": "1976",
      "journal-title": "Res Exp Med"
    },
    {
      "key": "10.1002/hep.1840050427-BIB32",
      "first-page": "604",
      "volume": "57",
      "author": "Nopanitaya",
      "year": "1976",
      "journal-title": "Br J Exp Pathol"
    },
    {
      "key": "10.1002/hep.1840050427-BIB33",
      "first-page": "213",
      "volume-title": "Kupffer cells and other liver sinusoidal cells",
      "author": "Frenzel",
      "year": "1977",
      "unstructured": ", . The liver sinusoids under various pathological conditions. A TEM and SEM study of rat liver after respiratory hypoxia, telecobalt-irradiation and endotoxin application. In: , eds. Kupffer cells and other liver sinusoidal cells. Amsterdam: Elsevier, 1977: 213\u2013222."
    },
    {
      "key": "10.1002/hep.1840050427-BIB34",
      "first-page": "195",
      "volume-title": "Proc Basler Liver Week 1979",
      "author": "Wisse",
      "year": "1980",
      "unstructured": ", . et al. On the role of the liver endothelial filter in the transport of particulate fat (chylomicrons and their remnants) to parenchymal cells and the influence of certain hormones on endothelial fenestrae. In: Proc Basler Liver Week 1979. London, England: MTP Press, 1980: 195\u2013200."
    },
    {
      "key": "10.1002/hep.1840050427-BIB35",
      "first-page": "105",
      "volume-title": "Intravital observation of organ microcirculation",
      "author": "Oda",
      "year": "1983",
      "unstructured": ", , et al. Some dynamic aspects of the hepatic microcirculation\u2013Demonstration of sinusoidal endothelial fenestrae as a possible regulatory factor. In: et al., eds. Intravital observation of organ microcirculation. The Hague: Excerpta Medica Foundation, 1983: 105\u2013138."
    },
    {
      "key": "10.1002/hep.1840050427-BIB36",
      "first-page": "5",
      "volume": "16",
      "author": "Oda",
      "year": "1983",
      "journal-title": "J Clin Electr Microsc"
    },
    {
      "key": "10.1002/hep.1840050427-BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "633",
      "DOI": "10.1083/jcb.37.3.633",
      "volume": "37",
      "author": "Palade",
      "year": "1968",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "10.1002/hep.1840050427-BIB38",
      "first-page": "79",
      "volume": "37",
      "author": "Ogawa",
      "year": "1983",
      "journal-title": "Acta Med Okayama"
    },
    {
      "key": "10.1002/hep.1840050427-BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "317",
      "DOI": "10.1016/0014-4827(77)90011-8",
      "volume": "109",
      "author": "Knook",
      "year": "1977",
      "journal-title": "Exp Cell Res"
    },
    {
      "key": "10.1002/hep.1840050427-BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "444",
      "DOI": "10.1016/0014-4827(76)90605-4",
      "volume": "99",
      "author": "Knook",
      "year": "1976",
      "journal-title": "Exp Cell Res"
    },
    {
      "key": "10.1002/hep.1840050427-BIB41",
      "first-page": "809",
      "volume": "292",
      "author": "Steffan",
      "year": "1981",
      "journal-title": "Comp Rend Acad Sci Paris"
    },
    {
      "key": "10.1002/hep.1840050427-BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "201",
      "DOI": "10.1007/BF00221510",
      "volume": "223",
      "author": "De Leeuw",
      "year": "1982",
      "journal-title": "Cell Tissue Res"
    },
    {
      "key": "10.1002/hep.1840050427-BIB43",
      "first-page": "647",
      "volume-title": "The liver: biology and pathobiology",
      "author": "Gumucio",
      "year": "1982",
      "unstructured": ". Liver cell heterogeneity. In: et al., eds. The liver: biology and pathobiology. New York: Raven Press, 1982: 647."
    },
    {
      "key": "10.1002/hep.1840050427-BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "455",
      "DOI": "10.1002/aja.1001190307",
      "volume": "199",
      "author": "McCuskey",
      "year": "1966",
      "journal-title": "Amer J Anat"
    },
    {
      "key": "10.1002/hep.1840050427-BIB45",
      "first-page": "73",
      "volume": "18",
      "author": "McCuskey",
      "year": "1979",
      "journal-title": "Biblio Anat"
    },
    {
      "key": "10.1002/hep.1840050427-BIB46",
      "first-page": "79",
      "volume": "59",
      "author": "McCuskey",
      "year": "1981",
      "journal-title": "Prog Clin Biol Res"
    },
    {
      "key": "10.1002/hep.1840050427-BIB47",
      "first-page": "57",
      "volume-title": "Microcirculation of the alimentary tract\u2013Physiology and pathophysiology",
      "author": "McCuskey",
      "year": "1983",
      "unstructured": "The hepatic microvascular system. In: , , eds. Microcirculation of the alimentary tract\u2013Physiology and pathophysiology. Singapore: World Science Publishing Co., 1983: 57\u201358."
    },
    {
      "key": "10.1002/hep.1840050427-BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "97",
      "DOI": "10.1002/aja.1001190107",
      "volume": "119",
      "author": "Heath",
      "year": "1966",
      "journal-title": "Amer J Anat"
    },
    {
      "key": "10.1002/hep.1840050427-BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "261",
      "DOI": "10.1113/expphysiol.1975.sp002320",
      "volume": "60",
      "author": "Koo",
      "year": "1975",
      "journal-title": "J Exp Physiol"
    }
  ],
  "container-title": "Hepatology",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fhep.1840050427",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://journals.lww.com/01515467-198507000-00026",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2024,
        12,
        1
      ]
    ],
    "date-time": "2024-12-01T11:11:13Z",
    "timestamp": 1733051473000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://journals.lww.com/01515467-198507000-00026"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1985,
        7
      ]
    ]
  },
  "references-count": 49,
  "journal-issue": {
    "issue": "4",
    "published-print": {
      "date-parts": [
        [
          1985
        ]
      ]
    }
  },
  "URL": "http://dx.doi.org/10.1002/hep.1840050427",
  "relation": {},
  "ISSN": [
    "0270-9139"
  ],
  "subject": [],
  "published": {
    "date-parts": [
      [
        1985,
        7
      ]
    ]
  }
}