DOI: 10.1002/cne.901830308. Patterns of cell proliferation in the retina of the clawed frog during development

Patterns of cell proliferation in the retina of the clawed frog during development

10.1002/cne.901830308

Crossref journal-article

Wiley

Journal of Comparative Neurology (311)

Abstract

AbstractQuantitative assays of the spatial pattern of cell production in the developing retina of Xenopus have been made using 3H‐thymidine labelling and colcemid blockade of mitosis. Reconstructions were made from serial sections showing the position of every mitotic figure in the retina. After stage 54 the number of mitotic figures decreases at the dorsal margin of the retina and increases at the ventral margin. The ventral:dorsal ratio of mitoses reaches 10:1 by metamorphosis. Density of mitotic figures is maximum at the point of entry of the ophthalmic vessels at the ventral margin. In spite of asymmetrical production of retinal cells the cell density remains constant throughout the retina, probably as a result of displacement of retinal cells dorsally to compensate for the relatively greater proliferation ventrally. It is also proposed that the asymmetrical retinal growth serves to maintain the relationship between each point in visual space and corresponding points in the two retinae as the eyes are displaced dorsally on the head during metamorphosis.

Bibliography

Beach, D. H., & Jacobson, M. (1979). Patterns of cell proliferation in the retina of the clawed frog during development. Journal of Comparative Neurology, 183(3), 603â613. Portico.

Authors 2

D. H. Beach (first)
Marcus Jacobson (additional)

References 23 Referenced 104

{'key': 'e_1_2_1_2_1', 'first-page': '83', 'article-title': 'Stretching of the retina during growth of salmon (Salmo salar)', 'volume': '28', 'author': 'Ali M. A.', 'year': '1964', 'journal-title': 'Growth'} / Growth / Stretching of the retina during growth of salmon (Salmo salar) by Ali M. A. (1964)
10.1016/0042-6989(72)90085-5
10.1002/cne.901830309
10.1002/cne.901830310
10.1002/aja.1000960106
10.1002/jez.1401330202
10.1098/rspb.1974.0021
10.1136/bjo.24.4.153
10.1038/269054a0
10.1007/BF02109662
10.1016/0012-1606(71)90098-4
10.1016/0012-1606(68)90062-6
10.1016/0006-8993(76)90452-2
10.1016/0006-8993(77)90379-1
10.1002/cne.901760303
10.1093/oxfordjournals.bmb.a071185 / Br. Med. Bull. / The role of visual function in the patterning of binocular visual connections by Keating M. H. (1974)
{'key': 'e_1_2_1_18_1', 'first-page': '915', 'article-title': 'Optics of Xenopus eyes during development. Appendix', 'volume': '33', 'author': 'Land M.', 'year': '1975', 'journal-title': 'J. Embryol. Morph.'} / J. Embryol. Morph. / Optics of Xenopus eyes during development. Appendix by Land M. (1975)
{'key': 'e_1_2_1_19_1', 'volume-title': 'Normal Table of Xenopus laevis (Daudin)', 'author': 'Nieuwkoop P. D.', 'year': '1956'} / Normal Table of Xenopus laevis (Daudin) by Nieuwkoop P. D. (1956)
10.1002/jmor.1051270307
{'key': 'e_1_2_1_21_1', 'first-page': '67', 'article-title': 'The growth of the retina of Xenopus laevis. An autoradiographic study', 'volume': '26', 'author': 'Straznicky K.', 'year': '1971', 'journal-title': 'J. Embryol. Exp. Morph.'} / J. Embryol. Exp. Morph. / The growth of the retina of Xenopus laevis. An autoradiographic study by Straznicky K. (1971)
{'key': 'e_1_2_1_22_1', 'first-page': '87', 'article-title': 'The development of the tectum in Xenopus laevis: An autoradiographic study', 'volume': '28', 'author': 'Straznicky K.', 'year': '1972', 'journal-title': 'J. Embryol. Exp. Morph.'} / J. Embryol. Exp. Morph. / The development of the tectum in Xenopus laevis: An autoradiographic study by Straznicky K. (1972)
{'key': 'e_1_2_1_23_1', 'first-page': '175', 'article-title': 'Retinal growth in double dorsal and double ventral eyes in\nXenopus', 'volume': '40', 'author': 'Straznicky K.', 'year': '1977', 'journal-title': 'J. Embryol. Exp. Morph.'} / J. Embryol. Exp. Morph. / Retinal growth in double dorsal and double ventral eyes in Xenopus by Straznicky K. (1977)
{'key': 'e_1_2_1_24_1', 'first-page': '245', 'article-title': 'The effect of mechanical stress on the differentiation of scleral cartilage in vitro and in the embryo', 'volume': '4', 'author': 'Weiss P.', 'year': '1940', 'journal-title': 'Growth'} / Growth / The effect of mechanical stress on the differentiation of scleral cartilage in vitro and in the embryo by Weiss P. (1940)

Dates

Type	When
Created	20 years, 7 months ago (Jan. 1, 2005, 1:31 p.m.)
Deposited	1 year, 9 months ago (Nov. 12, 2023, 6:54 p.m.)
Indexed	3 months, 1 week ago (May 15, 2025, 2:22 p.m.)
Issued	46 years, 6 months ago (Feb. 1, 1979)
Published	46 years, 6 months ago (Feb. 1, 1979)
Published Online	20 years, 10 months ago (Oct. 9, 2004)
Published Print	46 years, 6 months ago (Feb. 1, 1979)

Funders 0

None

BibTeX

@article{Beach_1979, title={Patterns of cell proliferation in the retina of the clawed frog during development}, volume={183}, ISSN={1096-9861}, url={http://dx.doi.org/10.1002/cne.901830308}, DOI={10.1002/cne.901830308}, number={3}, journal={Journal of Comparative Neurology}, publisher={Wiley}, author={Beach, D. H. and Jacobson, Marcus}, year={1979}, month=feb, pages={603–613} }

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