DOI: 10.1002/cbic.200200548. Mollusk Shell Acidic Proteins: In Search of Individual Functions

Mollusk Shell Acidic Proteins: In Search of Individual Functions

10.1002/cbic.200200548

Crossref journal-article

Wiley

ChemBioChem (311)

Abstract

AbstractAcidic proteins play a major role in the biomineralization process. These proteins are generally thought to control mineral formation and growth. Thus, characterization of individual acidic proteins is important as a first step toward linking function to individual proteins, which is our ultimate goal. In order to characterize the protein(s) responsible for the assemblage of biominerals, a new gel electrophoresis fixing and staining protocol was developed and many, if not all of the acidic proteins were visualized on the gel for the first time. In an in vitro assay we show that proteins extracted from an aragonitic shell layer induce the formation of amorphous calcium carbonate prior to its transformation into the aragonitic crystalline form. This study removes some major obstacles in the characterization of acidic proteins and sheds more light on the functions of these proteins in the biomineralization process.

Bibliography

Gotliv, B., Addadi, L., & Weiner, S. (2003). Mollusk Shell Acidic Proteins: In Search of Individual Functions. ChemBioChem, 4(6), 522â529. Portico.

Authors 3

Bat‐Ami Gotliv (first)
Lia Addadi (additional)
Steve Weiner (additional)

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Dates

Type	When
Created	22 years, 2 months ago (June 2, 2003, 11:05 a.m.)
Deposited	1 year, 10 months ago (Oct. 10, 2023, 9:30 p.m.)
Indexed	1 month ago (July 16, 2025, 8:28 a.m.)
Issued	22 years, 2 months ago (June 2, 2003)
Published	22 years, 2 months ago (June 2, 2003)
Published Online	22 years, 2 months ago (June 2, 2003)
Published Print	22 years, 2 months ago (June 6, 2003)

Funders 0

None

BibTeX

@article{Gotliv_2003, title={Mollusk Shell Acidic Proteins: In Search of Individual Functions}, volume={4}, ISSN={1439-7633}, url={http://dx.doi.org/10.1002/cbic.200200548}, DOI={10.1002/cbic.200200548}, number={6}, journal={ChemBioChem}, publisher={Wiley}, author={Gotliv, Bat‐Ami and Addadi, Lia and Weiner, Steve}, year={2003}, month=jun, pages={522–529} }

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