DOI: 10.1002/bip.360010504. Polynucleotides. VI. Molecular properties and conformation of polyribouridylic acid

Polynucleotides. VI. Molecular properties and conformation of polyribouridylic acid

10.1002/bip.360010504

Crossref journal-article

Wiley

Biopolymers (311)

Abstract

AbstractOptical, hydrodynamic, and titration properties of polyribouridylic acid (poly U) were investigated in 0.2M Na+, pH 6. Above 15°C., poly U was shown to be a randomly coiled single chain, devoid of secondary structure. There is no shear rate dependence of viscosity; molecular weight is independent of ionic strength; there is virtually no conformationally dependent hypochromicity; no anomalous optical rotatory dispersion; and no anomalous titration behavior. The dependence of the sedimentation constant and intrinsic viscosity on molecular weight was determined. Poly U was shown to be the most highly expanded of all synthetic and naturally occurring randomly coiled polynucleotides.

Bibliography

Richards, E. G., Flessel, C. P., & Fresco, J. R. (1963). Polynucleotides. VI. Molecular properties and conformation of polyribouridylic acid. Biopolymers, 1(5), 431â446. Portico.

Authors 3

Edward G. Richards (first)
C. Peter Flessel (additional)
Jacques R. Fresco (additional)

References 44 Referenced 132

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{'key': 'e_1_2_1_4_2', 'first-page': '557', 'volume-title': 'The Chemical Basis of Heredity', 'author': 'Rich A.', 'year': '1957'} / The Chemical Basis of Heredity by Rich A. (1957)
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{'key': 'e_1_2_1_10_2', 'first-page': '628', 'volume-title': 'Principles of Polymer Chemistry', 'author': 'Flory P. J.', 'year': '1953'} / Principles of Polymer Chemistry by Flory P. J. (1953)
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{'key': 'e_1_2_1_17_2', 'first-page': '513', 'volume-title': 'The Nucleic Acids', 'author': 'Beaven G. H.', 'year': '1955'} / The Nucleic Acids by Beaven G. H. (1955)
{'key': 'e_1_2_1_18_2', 'first-page': '446', 'volume-title': 'The Chemistry of Nucleosides and Nucleotides', 'author': 'Michelson A. M.', 'year': '1963'} / The Chemistry of Nucleosides and Nucleotides by Michelson A. M. (1963)
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Fresco J. R. R.Brown andP.Doty in preparation.
10.1016/0006-3002(59)90137-4
{'key': 'e_1_2_1_27_2', 'first-page': '157', 'volume': '9', 'author': 'Warner R. C.', 'year': '1958', 'journal-title': 'Proc. Intern. Congr. Biochem., 4th, Vienna'} / Proc. Intern. Congr. Biochem., 4th, Vienna by Warner R. C. (1958)
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{'key': 'e_1_2_1_30_2', 'first-page': '155', 'volume-title': 'Proteins, Amino Acids and Peptides', 'author': 'Cohn E. J.', 'year': '1943'} / Proteins, Amino Acids and Peptides by Cohn E. J. (1943)
{'key': 'e_1_2_1_31_2', 'first-page': '23', 'volume': '12', 'author': 'Spiegelman S.', 'year': '1959', 'journal-title': 'Brookhaven Symp. Biol.'} / Brookhaven Symp. Biol. by Spiegelman S. (1959)
{'key': 'e_1_2_1_32_2', 'first-page': '93', 'volume-title': 'Acides Ribonucleique et Polyphosphates. Structure, Synthese et Fonctiones', 'author': 'Möller W.', 'year': '1962'} / Acides Ribonucleique et Polyphosphates. Structure, Synthese et Fonctiones by Möller W. (1962)
10.1016/0042-6822(61)90131-3
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See ref. 9 p.311 and chapter XIV.
{'key': 'e_1_2_1_36_2', 'first-page': '27', 'volume-title': 'Microsomal Particles and Protein Synthesis', 'author': 'Hall B. D.', 'year': '1958'} / Microsomal Particles and Protein Synthesis by Hall B. D. (1958)
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{'key': 'e_1_2_1_39_2', 'first-page': '6186', 'volume': '80', 'author': 'Strauss U. P.', 'year': '1958', 'journal-title': 'J. Am. Chem. Soc.'} / J. Am. Chem. Soc. by Strauss U. P. (1958)
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10.1146/annurev.bi.31.070162.001505
See ref. 9 p.321.

Dates

Type	When
Created	20 years, 7 months ago (Dec. 29, 2004, 7:19 p.m.)
Deposited	1 year, 9 months ago (Nov. 12, 2023, 6:08 a.m.)
Indexed	1 year, 3 months ago (April 30, 2024, 11:16 a.m.)
Issued	61 years, 10 months ago (Oct. 1, 1963)
Published	61 years, 10 months ago (Oct. 1, 1963)
Published Online	21 years, 6 months ago (Feb. 1, 2004)
Published Print	61 years, 10 months ago (Oct. 1, 1963)

Funders 0

None

BibTeX

@article{Richards_1963, title={Polynucleotides. VI. Molecular properties and conformation of polyribouridylic acid}, volume={1}, ISSN={1097-0282}, url={http://dx.doi.org/10.1002/bip.360010504}, DOI={10.1002/bip.360010504}, number={5}, journal={Biopolymers}, publisher={Wiley}, author={Richards, Edward G. and Flessel, C. Peter and Fresco, Jacques R.}, year={1963}, month=oct, pages={431–446} }

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