DOI: 10.1002/bies.950180907. Connexins in mammalian heart function

10.1002/bies.950180907

Crossref journal-article

Wiley

BioEssays (311)

Abstract

AbstractIn heart, the propagation of electrical activity is mediated by intercellular channels, referred to as junctional channels, aggregated into gap junctions and localised between myocytes. These channels consist of structurally related transmembrane proteins, the connexins, three of which (CX43, CX40 and CX45) have been shown to be associated with the myocytes of mammalian heart; a fourth, CX37, was detected exclusively in endothelial cells. In this paper, we review the recent data dealing with the topographical heterogeneity of expression of these connexins in the different cardiac tissues and the unique conductance properties of the channels they form, and attempt to assess the role played by each connexin and the consequences of their multiplicity in the propagation of action potentials.

Bibliography

Gros, D. B., & Jongsma, H. J. (1996). Connexins in mammalian heart function. BioEssays, 18(9), 719â730. Portico.

Authors 2

Daniel B. Gros (first)
Habo J. Jongsma (additional)

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Dates

Type	When
Created	20 years, 6 months ago (Feb. 25, 2005, 5:53 a.m.)
Deposited	1 year, 10 months ago (Oct. 27, 2023, 10:25 a.m.)
Indexed	1 month, 4 weeks ago (July 2, 2025, 2:32 p.m.)
Issued	29 years ago (Sept. 1, 1996)
Published	29 years ago (Sept. 1, 1996)
Published Online	20 years, 6 months ago (Feb. 5, 2005)
Published Print	29 years ago (Sept. 1, 1996)

Funders 0

None

BibTeX

@article{Gros_1996, title={Connexins in mammalian heart function}, volume={18}, ISSN={1521-1878}, url={http://dx.doi.org/10.1002/bies.950180907}, DOI={10.1002/bies.950180907}, number={9}, journal={BioEssays}, publisher={Wiley}, author={Gros, Daniel B. and Jongsma, Habo J.}, year={1996}, month=sep, pages={719–730} }

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