DOI: 10.1002/bies.950171109. Stress signaling in yeast

10.1002/bies.950171109

Crossref journal-article

Wiley

BioEssays (311)

Abstract

AbstractIn the yeast Saccharomyces cerevisiae three positive transcriptional control elements are activated by stress conditions: heat shock elements (HSEs), stress response elements (STREs) and AP‐1 responsive elements (AREs). HSEs bind heat shock transcription factor (HSF), which is activated by stress conditions causing accumulation of abnormal proteins. STREs mediate transcriptional activation by multiple stress conditions. They are controlled by high osmolarity via the HOG signal pathway, which comprises a MAP kinase module and a two‐component system homologous to prokaryotic signal transducers. AREs bind the transcription factor Yap1p. The three types of control elements seem to have overlapping, but distinct functions. Some stress proteins encoded by HSE‐regulated genes are necessary for growth of yeast under moderate stress, products of STRE‐activated genes appear to be important for survival under severe stress and ARE‐controlled genes may mainly function during oxidative stress and in the response to toxic conditions, such as caused by heavy metal ions.

Bibliography

Ruis, H., & SchÃ¼ller, C. (1995). Stress signaling in yeast. BioEssays, 17(11), 959â965. Portico.

Authors 2

Helmut Ruis (first)
Christoph Schüller (additional)

References 74 Referenced 314

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Dates

Type	When
Created	20 years, 6 months ago (Feb. 25, 2005, 5:04 a.m.)
Deposited	1 year, 10 months ago (Oct. 27, 2023, 12:05 a.m.)
Indexed	2 days, 19 hours ago (Aug. 28, 2025, 8:12 a.m.)
Issued	29 years, 9 months ago (Nov. 1, 1995)
Published	29 years, 9 months ago (Nov. 1, 1995)
Published Online	20 years, 6 months ago (Feb. 5, 2005)
Published Print	29 years, 9 months ago (Nov. 1, 1995)

Funders 0

None

BibTeX

@article{Ruis_1995, title={Stress signaling in yeast}, volume={17}, ISSN={1521-1878}, url={http://dx.doi.org/10.1002/bies.950171109}, DOI={10.1002/bies.950171109}, number={11}, journal={BioEssays}, publisher={Wiley}, author={Ruis, Helmut and Schüller, Christoph}, year={1995}, month=nov, pages={959–965} }

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