DOI: 10.1002/bies.950170810. Instability of inhibited replication forks in <i>E. coli</i>

Instability of inhibited replication forks in E. coli

10.1002/bies.950170810

Crossref journal-article

Wiley

BioEssays (311)

Abstract

AbstractInhibiting the progress of replication forks in E. coli makes them susceptible to breakage. Broken replication forks are evidently reassembled by the RecBCD recombinational repair pathway. These findings explain a particular pattern of DNA degradation during inhibition of chromosomal replication, the role of recombination in the viability of mutants with displaced replication origin, and hyper‐recombination observed in the Terminus of the E. coli chromosome in rnh mutants. Breakage and repair of inhibited replication forks could be the reason for the recombination‐dependence of inducible stable DNA replication. A mechanism by which RecABCD‐dependent recombination between very short inverted repeats may help E. coli to invert an operon, transcribed in the direction opposite to that of DNA replication, is discussed.

Bibliography

Kuzminov, A. (1995). Instability of inhibited replication forks in E. coli. BioEssays, 17(8), 733â741. Portico.

Authors 1

Andrei Kuzminov (first)

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Dates

Type	When
Created	20 years, 6 months ago (Feb. 25, 2005, 4:10 a.m.)
Deposited	1 year, 10 months ago (Oct. 25, 2023, 2:56 p.m.)
Indexed	4 months, 3 weeks ago (April 16, 2025, 6:47 a.m.)
Issued	30 years, 1 month ago (Aug. 1, 1995)
Published	30 years, 1 month ago (Aug. 1, 1995)
Published Online	20 years, 7 months ago (Feb. 5, 2005)
Published Print	30 years, 1 month ago (Aug. 1, 1995)

Funders 0

None

BibTeX

@article{Kuzminov_1995, title={Instability of inhibited replication forks in E. coli}, volume={17}, ISSN={1521-1878}, url={http://dx.doi.org/10.1002/bies.950170810}, DOI={10.1002/bies.950170810}, number={8}, journal={BioEssays}, publisher={Wiley}, author={Kuzminov, Andrei}, year={1995}, month=aug, pages={733–741} }

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