DOI: 10.1002/bies.950170112. Are there DNA damage checkpoints in <i>E. coli</i>?

Are there DNA damage checkpoints in E. coli?

10.1002/bies.950170112

Crossref journal-article

Wiley

BioEssays (311)

Abstract

AbstractThe concept of regulatory ‘checkpoints’ in the eukaryotic cycle has proved to be a fruitful one. Here, its applicability to the bacterial cell cycle is examined. A primitive DNA damage checkpoint operates in E. coli such that, after exposure to ultraviolet light, while excision repair occurs, chromosome replication continues very slowly with the production of discontinuous daughter strands. The slower the rate of excision of photoproducts, the greater the delay before the normal rate of DNA replication is restored, the additional time for repair ensuring that normal survival is maintained. A model is proposed in which replication rate is controlled by the ratio of RecAcoated to uncoated single stranded regions of DNA in the replication fork. There are also two cell division inhibitors SulA (=SfiA) and SfiC under the control of the SOS system and sensitive to DNA damage, but they are irrelevant to the survival of wild‐type bacteria under normal conditions. In strains where SulA and SfiC do not operate, inhibition is not influenced by the rate of excision repair and so fails one of the criteria for a DNA damage checkpoint, namely the monitoring of the DNA for the level of residual damage.

Bibliography

Bridges, B. A. (1995). Are there DNA damage checkpoints in E. coli? BioEssays, 17(1), 63â70. Portico.

Authors 1

Bryn A. Bridges (first)

References 50 Referenced 19

10.1099/00221287-18-2-461
10.1093/infdis/114.3.235
10.1007/BF00332704
10.1016/0027-5107(75)90229-8
10.1016/0027-5107(75)90067-6
{'key': 'e_1_2_1_7_2', 'first-page': '393', 'article-title': 'Error‐prone DNA repair in Escherichia coli. IV', 'volume': '95', 'author': 'Bridges B. A.', 'year': '1976', 'journal-title': 'Biol. Zbl.'} / Biol. Zbl. / Error‐prone DNA repair in Escherichia coli. IV by Bridges B. A. (1976)
10.1126/science.3291120
10.1016/0092-8674(87)90183-8
10.1111/j.1365-2958.1991.tb00747.x
10.1146/annurev.mi.47.100193.001215
10.1093/genetics/53.6.1137 / Genetics / Mutants of Escherichia coli K12 deficient in DNA repair and in genetic recombination by Howard‐Flanders P. (1966)
10.1073/pnas.45.5.709
10.2307/3571988
10.1016/0027-5107(69)90065-7
10.1126/science.142.3598.1464
10.1007/BF00327522
10.1038/249348a0
10.1016/0022-2836(68)90445-2
10.1073/pnas.88.24.11574
George D. L.(1974).Characterization of a mutant ofEscherichia coliB/r defective in mutation frequency decline. PhD Thesis Rutgers University New Brunswick NJ USA.
10.1002/9780470719718.ch4
{'key': 'e_1_2_1_23_2', 'first-page': '52', 'article-title': 'Evidence for a further dark repair process in bacteria', 'volume': '139', 'author': 'Bridges B. A.', 'year': '1972', 'journal-title': 'Nature'} / Nature / Evidence for a further dark repair process in bacteria by Bridges B. A. (1972)
10.1016/0027-5107(73)90247-9
10.1073/pnas.84.19.6805
10.1080/09553008914550791
10.1007/BF00326074
10.1007/BF00331171
10.1038/305243a0
10.1016/0147-619X(89)90026-7
10.1006/jmbi.1993.1644
10.1073/pnas.57.5.1275
10.1128/jb.96.5.1704-1710.1968 / J. Bacteriol. / Interaction of the exr and lon genes in Escherichia coli by Donch J. (1968)
10.1073/pnas.81.14.4490
10.1128/jb.154.3.1339-1346.1983 / J. Bacteriol. / Coupling of DNA replication and cell division:sulB is an allele of ftsZ by Lutkenhaus J. F. (1983)
10.1073/pnas.82.18.6045
{'key': 'e_1_2_1_37_2', 'first-page': '165', 'article-title': 'The role of the FtsZ protein (SfiB) in UV‐induced division inhibition and in the normal Escherichia coli cell division cycle', 'volume': '136', 'author': 'Holland I. B.', 'year': '1985', 'journal-title': 'Ann. Microbiol. (Paris).'} / Ann. Microbiol. (Paris). / The role of the FtsZ protein (SfiB) in UV‐induced division inhibition and in the normal Escherichia coli cell division cycle by Holland I. B. (1985)
10.1128/jb.123.2.693-703.1975 / J. Bacteriol. / Regulation of bacterial cell division: temperature‐sensitive mutants of Escherichia coli that are defective in septum formation by Walker J. R. (1975)
10.1128/jb.163.2.615-622.1985
10.1016/0092-8674(85)90290-9
10.1007/BF00330334
10.1128/jb.144.1.185-191.1980 / J. Bacteriol. / Further characterization of sfiA and sfiB mutations in Escherichia coli by Huisman O. (1980)
10.1128/jb.168.1.464-466.1986
10.1128/jb.165.1.66-71.1986
10.1016/0022-2836(68)90425-7
10.1038/243100a0
10.1128/jb.114.2.824-837.1973 / J. Bacteriol. / Changes in cell size and shape associated with changes in the replication time of the chromosome of E coli by Zaritsky A. (1973)
10.1128/jb.171.1.74-79.1989
10.1016/0092-8674(90)90588-6
10.1016/0143-4160(89)90012-2
10.1038/210922a0

Dates

Type	When
Created	20 years, 6 months ago (Feb. 25, 2005, 4:59 a.m.)
Deposited	1 year, 10 months ago (Oct. 25, 2023, 8:14 p.m.)
Indexed	1 year, 7 months ago (Jan. 18, 2024, 12:23 a.m.)
Issued	30 years, 7 months ago (Jan. 1, 1995)
Published	30 years, 7 months ago (Jan. 1, 1995)
Published Online	20 years, 6 months ago (Feb. 5, 2005)
Published Print	30 years, 7 months ago (Jan. 1, 1995)

Funders 0

None

BibTeX

@article{Bridges_1995, title={Are there DNA damage checkpoints in E. coli?}, volume={17}, ISSN={1521-1878}, url={http://dx.doi.org/10.1002/bies.950170112}, DOI={10.1002/bies.950170112}, number={1}, journal={BioEssays}, publisher={Wiley}, author={Bridges, Bryn A.}, year={1995}, month=jan, pages={63–70} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2024,
        1,
        18
      ]
    ],
    "date-time": "2024-01-18T05:23:53Z",
    "timestamp": 1705555433829
  },
  "reference-count": 50,
  "publisher": "Wiley",
  "issue": "1",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2005,
            2,
            5
          ]
        ],
        "date-time": "2005-02-05T00:00:00Z",
        "timestamp": 1107561600000
      },
      "content-version": "vor",
      "delay-in-days": 3688,
      "URL": "http://onlinelibrary.wiley.com/termsAndConditions#vor"
    }
  ],
  "content-domain": {
    "domain": [
      "onlinelibrary.wiley.com"
    ],
    "crossmark-restriction": true
  },
  "published-print": {
    "date-parts": [
      [
        1995,
        1
      ]
    ]
  },
  "abstract": "<jats:title>Abstract</jats:title><jats:p>The concept of regulatory \u2018checkpoints\u2019 in the eukaryotic cycle has proved to be a fruitful one. Here, its applicability to the bacterial cell cycle is examined. A primitive DNA damage checkpoint operates in <jats:italic>E. coli</jats:italic> such that, after exposure to ultraviolet light, while excision repair occurs, chromosome replication continues very slowly with the production of discontinuous daughter strands. The slower the rate of excision of photoproducts, the greater the delay before the normal rate of DNA replication is restored, the additional time for repair ensuring that normal survival is maintained. A model is proposed in which replication rate is controlled by the ratio of RecAcoated to uncoated single stranded regions of DNA in the replication fork. There are also two cell division inhibitors SulA (=SfiA) and SfiC under the control of the SOS system and sensitive to DNA damage, but they are irrelevant to the survival of wild\u2010type bacteria under normal conditions. In strains where SulA and SfiC do not operate, inhibition is not influenced by the rate of excision repair and so fails one of the criteria for a DNA damage checkpoint, namely the monitoring of the DNA for the level of residual damage.</jats:p>",
  "DOI": "10.1002/bies.950170112",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2005,
        2,
        25
      ]
    ],
    "date-time": "2005-02-25T09:59:33Z",
    "timestamp": 1109325573000
  },
  "page": "63-70",
  "update-policy": "http://dx.doi.org/10.1002/crossmark_policy",
  "source": "Crossref",
  "is-referenced-by-count": 19,
  "title": "Are there DNA damage checkpoints in <i>E. coli</i>?",
  "prefix": "10.1002",
  "volume": "17",
  "author": [
    {
      "given": "Bryn A.",
      "family": "Bridges",
      "sequence": "first",
      "affiliation": []
    }
  ],
  "member": "311",
  "published-online": {
    "date-parts": [
      [
        2005,
        2,
        5
      ]
    ]
  },
  "reference": [
    {
      "key": "e_1_2_1_2_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1099/00221287-18-2-461"
    },
    {
      "key": "e_1_2_1_3_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1093/infdis/114.3.235"
    },
    {
      "key": "e_1_2_1_4_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1007/BF00332704"
    },
    {
      "key": "e_1_2_1_5_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0027-5107(75)90229-8"
    },
    {
      "key": "e_1_2_1_6_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0027-5107(75)90067-6"
    },
    {
      "key": "e_1_2_1_7_2",
      "first-page": "393",
      "article-title": "Error\u2010prone DNA repair in Escherichia coli. IV",
      "volume": "95",
      "author": "Bridges B. A.",
      "year": "1976",
      "journal-title": "Biol. Zbl."
    },
    {
      "key": "e_1_2_1_8_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.3291120"
    },
    {
      "key": "e_1_2_1_9_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(87)90183-8"
    },
    {
      "key": "e_1_2_1_10_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1111/j.1365-2958.1991.tb00747.x"
    },
    {
      "key": "e_1_2_1_11_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1146/annurev.mi.47.100193.001215"
    },
    {
      "key": "e_1_2_1_12_2",
      "doi-asserted-by": "crossref",
      "first-page": "1137",
      "DOI": "10.1093/genetics/53.6.1137",
      "article-title": "Mutants of Escherichia coli K12 deficient in DNA repair and in genetic recombination",
      "volume": "53",
      "author": "Howard\u2010Flanders P.",
      "year": "1966",
      "journal-title": "Genetics"
    },
    {
      "key": "e_1_2_1_13_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.45.5.709"
    },
    {
      "key": "e_1_2_1_14_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.2307/3571988"
    },
    {
      "key": "e_1_2_1_15_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0027-5107(69)90065-7"
    },
    {
      "key": "e_1_2_1_16_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.142.3598.1464"
    },
    {
      "key": "e_1_2_1_17_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1007/BF00327522"
    },
    {
      "key": "e_1_2_1_18_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/249348a0"
    },
    {
      "key": "e_1_2_1_19_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0022-2836(68)90445-2"
    },
    {
      "key": "e_1_2_1_20_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.88.24.11574"
    },
    {
      "key": "e_1_2_1_21_2",
      "unstructured": "George D. L.(1974).Characterization of a mutant ofEscherichia coliB/r defective in mutation frequency decline. PhD Thesis Rutgers University New Brunswick NJ USA."
    },
    {
      "key": "e_1_2_1_22_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/9780470719718.ch4"
    },
    {
      "key": "e_1_2_1_23_2",
      "first-page": "52",
      "article-title": "Evidence for a further dark repair process in bacteria",
      "volume": "139",
      "author": "Bridges B. A.",
      "year": "1972",
      "journal-title": "Nature"
    },
    {
      "key": "e_1_2_1_24_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0027-5107(73)90247-9"
    },
    {
      "key": "e_1_2_1_25_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.84.19.6805"
    },
    {
      "key": "e_1_2_1_26_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1080/09553008914550791"
    },
    {
      "key": "e_1_2_1_27_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1007/BF00326074"
    },
    {
      "key": "e_1_2_1_28_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1007/BF00331171"
    },
    {
      "key": "e_1_2_1_29_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/305243a0"
    },
    {
      "key": "e_1_2_1_30_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0147-619X(89)90026-7"
    },
    {
      "key": "e_1_2_1_31_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1006/jmbi.1993.1644"
    },
    {
      "key": "e_1_2_1_32_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.57.5.1275"
    },
    {
      "key": "e_1_2_1_33_2",
      "doi-asserted-by": "crossref",
      "first-page": "1704",
      "DOI": "10.1128/jb.96.5.1704-1710.1968",
      "article-title": "Interaction of the exr and lon genes in Escherichia coli",
      "volume": "96",
      "author": "Donch J.",
      "year": "1968",
      "journal-title": "J. Bacteriol."
    },
    {
      "key": "e_1_2_1_34_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.81.14.4490"
    },
    {
      "key": "e_1_2_1_35_2",
      "doi-asserted-by": "crossref",
      "first-page": "1339",
      "DOI": "10.1128/jb.154.3.1339-1346.1983",
      "article-title": "Coupling of DNA replication and cell division:sulB is an allele of ftsZ",
      "volume": "154",
      "author": "Lutkenhaus J. F.",
      "year": "1983",
      "journal-title": "J. Bacteriol."
    },
    {
      "key": "e_1_2_1_36_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.82.18.6045"
    },
    {
      "key": "e_1_2_1_37_2",
      "first-page": "165",
      "article-title": "The role of the FtsZ protein (SfiB) in UV\u2010induced division inhibition and in the normal Escherichia coli cell division cycle",
      "volume": "136",
      "author": "Holland I. B.",
      "year": "1985",
      "journal-title": "Ann. Microbiol. (Paris)."
    },
    {
      "key": "e_1_2_1_38_2",
      "doi-asserted-by": "crossref",
      "first-page": "693",
      "DOI": "10.1128/jb.123.2.693-703.1975",
      "article-title": "Regulation of bacterial cell division: temperature\u2010sensitive mutants of Escherichia coli that are defective in septum formation",
      "volume": "123",
      "author": "Walker J. R.",
      "year": "1975",
      "journal-title": "J. Bacteriol."
    },
    {
      "key": "e_1_2_1_39_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1128/jb.163.2.615-622.1985"
    },
    {
      "key": "e_1_2_1_40_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(85)90290-9"
    },
    {
      "key": "e_1_2_1_41_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1007/BF00330334"
    },
    {
      "key": "e_1_2_1_42_2",
      "doi-asserted-by": "crossref",
      "first-page": "185",
      "DOI": "10.1128/jb.144.1.185-191.1980",
      "article-title": "Further characterization of sfiA and sfiB mutations in Escherichia coli",
      "volume": "144",
      "author": "Huisman O.",
      "year": "1980",
      "journal-title": "J. Bacteriol."
    },
    {
      "key": "e_1_2_1_43_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1128/jb.168.1.464-466.1986"
    },
    {
      "key": "e_1_2_1_44_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1128/jb.165.1.66-71.1986"
    },
    {
      "key": "e_1_2_1_45_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0022-2836(68)90425-7"
    },
    {
      "key": "e_1_2_1_46_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/243100a0"
    },
    {
      "key": "e_1_2_1_47_2",
      "doi-asserted-by": "crossref",
      "first-page": "824",
      "DOI": "10.1128/jb.114.2.824-837.1973",
      "article-title": "Changes in cell size and shape associated with changes in the replication time of the chromosome of E coli",
      "volume": "144",
      "author": "Zaritsky A.",
      "year": "1973",
      "journal-title": "J. Bacteriol."
    },
    {
      "key": "e_1_2_1_48_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1128/jb.171.1.74-79.1989"
    },
    {
      "key": "e_1_2_1_49_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(90)90588-6"
    },
    {
      "key": "e_1_2_1_50_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0143-4160(89)90012-2"
    },
    {
      "key": "e_1_2_1_51_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/210922a0"
    }
  ],
  "container-title": "BioEssays",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbies.950170112",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://onlinelibrary.wiley.com/doi/pdf/10.1002/bies.950170112",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        10,
        26
      ]
    ],
    "date-time": "2023-10-26T00:14:28Z",
    "timestamp": 1698279268000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://onlinelibrary.wiley.com/doi/10.1002/bies.950170112"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1995,
        1
      ]
    ]
  },
  "references-count": 50,
  "journal-issue": {
    "issue": "1",
    "published-print": {
      "date-parts": [
        [
          1995,
          1
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1002/bies.950170112"
  ],
  "URL": "http://dx.doi.org/10.1002/bies.950170112",
  "relation": {},
  "ISSN": [
    "0265-9247",
    "1521-1878"
  ],
  "subject": [],
  "container-title-short": "BioEssays",
  "published": {
    "date-parts": [
      [
        1995,
        1
      ]
    ]
  },
  "assertion": [
    {
      "value": "1994-08-30",
      "order": 1,
      "name": "accepted",
      "label": "Accepted",
      "group": {
        "name": "publication_history",
        "label": "Publication History"
      }
    },
    {
      "value": "2005-02-05",
      "order": 2,
      "name": "published",
      "label": "Published",
      "group": {
        "name": "publication_history",
        "label": "Publication History"
      }
    }
  ]
}