DOI: 10.1002/bies.950131004. Expression patterns of mouse hox genes: Clues to an understanding of developmental and evolutionary strategies

Expression patterns of mouse hox genes: Clues to an understanding of developmental and evolutionary strategies

10.1002/bies.950131004

Crossref journal-article

Wiley

BioEssays (311)

Abstract

AbstractExpression patterns of Antennapedia‐like homeogenes in the mouse embryo show many similarities to those of their homologues in Drosophila. It is argued here that homeogenes may regulate development of the body plan in mouse by mechanisms similar to those used in Drosophila. In particular, they may differentially specify positional address of cell groups within lineage compartments along the body axes. In vertebrates, a single ancestral homeogene cluster has become duplicated to give four separate clusters. Comparisons of homeogene expression patterns between different clusters of the mouse suggest ways in which duplication has permitted development of a more complex body plan. Cluster duplication may therefore have provided a selective advantage during vertebrate evolution.

Bibliography

Gaunt, S. J. (1991). Expression patterns of mouse hox genes: Clues to an understanding of developmental and evolutionary strategies. BioEssays, 13(10), 505â513. Portico.

Authors 1

Stephen J. Gaunt (first)

References 62 Referenced 72

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Dates

Type	When
Created	20 years, 6 months ago (Feb. 25, 2005, 5:30 a.m.)
Deposited	1 year, 10 months ago (Oct. 23, 2023, 11:53 a.m.)
Indexed	1 year ago (Aug. 9, 2024, 1:51 p.m.)
Issued	33 years, 11 months ago (Oct. 1, 1991)
Published	33 years, 11 months ago (Oct. 1, 1991)
Published Online	20 years, 6 months ago (Feb. 5, 2005)
Published Print	33 years, 11 months ago (Oct. 1, 1991)

Funders 0

None

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