Abstract
AbstractGrowth cones are the highly motile structures found at the tips of growing axons and dendrites (neurites), which extend from neurones, during the development of the nervous system. They function both as detectors and transducers of extrinsic guidance cues and as regions where the neurite cytoskeleton is assembled. Without concerted neurite assembly, advance cannot occur. Assembly of the neurite cytoskeleton in growing neurites chiefly involves microtubule assembly at the growth cone. Some of the factors that may influence microtubule assembly in growth cones are becoming apparent and include posttranslational modification of tubulin itself and microtubule associated proteins, particularly tau and MAP1B.
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Dates
Type | When |
---|---|
Created | 20 years, 6 months ago (Feb. 25, 2005, 6:15 a.m.) |
Deposited | 1 year, 10 months ago (Oct. 22, 2023, 7:17 p.m.) |
Indexed | 2 months, 3 weeks ago (June 12, 2025, 5:26 a.m.) |
Issued | 34 years, 4 months ago (May 1, 1991) |
Published | 34 years, 4 months ago (May 1, 1991) |
Published Online | 20 years, 7 months ago (Feb. 5, 2005) |
Published Print | 34 years, 4 months ago (May 1, 1991) |
@article{Gordon_Weeks_1991, title={Growth cones: The mechanism of neurite advance}, volume={13}, ISSN={1521-1878}, url={http://dx.doi.org/10.1002/bies.950130506}, DOI={10.1002/bies.950130506}, number={5}, journal={BioEssays}, publisher={Wiley}, author={Gordon‐Weeks, P. R.}, year={1991}, month=may, pages={235–239} }