10.1002/bies.950120803
Crossref journal-article
Wiley
BioEssays (311)
Abstract

AbstractEukaryotic chromosomes end with tandem repeats of simple sequences. These GC rich repeats allow telomere replication and stabilize chromosome ends. Telomere replication involves an equilibrium of sequence loss and addition at the ends of chromosomes. Repeats are added de novo by telomerase, an unusual DNA polymerase. Telomerase is an RNP in which an essential RNA component provides the template for the added telomere repeats. Telomere length maintenance plays an essential role in cell viability.

Bibliography

Greider, C. W. (1990). Telomeres, telomerase and senescence. BioEssays, 12(8), 363–369. Portico.

Authors 1
  1. Carol W. Greider (first)
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Dates
Type When
Created 20 years, 6 months ago (Feb. 25, 2005, 6:22 a.m.)
Deposited 1 year, 10 months ago (Oct. 22, 2023, 1:27 p.m.)
Indexed 2 months, 3 weeks ago (June 7, 2025, 12:28 a.m.)
Issued 35 years ago (Aug. 1, 1990)
Published 35 years ago (Aug. 1, 1990)
Published Online 20 years, 6 months ago (Feb. 5, 2005)
Published Print 35 years ago (Aug. 1, 1990)
Funders 0

None

@article{Greider_1990, title={Telomeres, telomerase and senescence}, volume={12}, ISSN={1521-1878}, url={http://dx.doi.org/10.1002/bies.950120803}, DOI={10.1002/bies.950120803}, number={8}, journal={BioEssays}, publisher={Wiley}, author={Greider, Carol W.}, year={1990}, month=aug, pages={363–369} }