DOI: 10.1002/bies.950040308. Structural and functional domains on actin

Structural and functional domains on actin

10.1002/bies.950040308

Crossref journal-article

Wiley

BioEssays (311)

Abstract

AbstractActin plays several essential roles in cellular processes and is a vital component in the contractile apparatus. To accomplish its many cellular tasks, actin must interact with a wide range of other proteins in addition to self‐assembling into filaments. Characterization of these functional domains and localized binding regions on the actin monomer is therefore an important undertaking. Strategies for elucidating the many interaction sites include X‐ray diffraction, NMR and fluorescence spectroscopy, chemical modification, chemical cross‐linking, protein cleavage, and the study of sequence homologies between the many isotypes of actin. Based on these varied data, we discuss the possible spatial relationships between the interaction sites.

Bibliography

Hambly, B. D., Barden, J. A., Miki, M., & Dos Remedios, C. G. (1986). Structural and functional domains on actin. BioEssays, 4(3), 124â128. Portico.

Authors 4

Brett D. Hambly (first)
Julian A. Barden (additional)
Masao Miki (additional)
Cristobal G. Dos Remedios (additional)

References 30 Referenced 29

10.1016/0022-2836(84)90072-X
10.1016/B978-0-12-673001-2.50009-4
10.1016/0141-8130(82)90025-3
10.1021/bi00523a040
10.1016/0167-4838(84)90281-4
{'key': 'e_1_2_1_7_2', 'first-page': '583', 'article-title': 'Fluorescence energy transfer between Tyr‐69 and Cys‐374 in actin', 'volume': '11', 'author': 'Barden J. A.', 'year': '1985', 'journal-title': 'Biochem. Int.'} / Biochem. Int. / Fluorescence energy transfer between Tyr‐69 and Cys‐374 in actin by Barden J. A. (1985)
10.1016/S0021-9258(18)33549-X / J. Biol. Chem. / Changes in actin lysine reactivities during polymerization detected using a competitive labelling method by Hitchcock‐De Gregori S. E. (1982)
{'key': 'e_1_2_1_9_2', 'first-page': '74', 'volume': '6', 'author': 'ABSTRACTS OF THE THIRTEENTH EUROPEAN CONFERENCE ON MUSCLE AND MOTILITY', 'year': '1985', 'journal-title': 'J. Muscle Res. Cell Motil.'} / J. Muscle Res. Cell Motil. by ABSTRACTS OF THE THIRTEENTH EUROPEAN CONFERENCE ON MUSCLE AND MOTILITY (1985)
10.1073/pnas.81.21.6599
10.1021/bi00304a009
10.1016/0167-4838(85)90003-2
10.1083/jcb.89.2.362
10.1016/0167-4838(85)90056-1
10.1016/0167-4838(84)90088-8
Barden J. A.&Miki M.(1986). The distances separating Tyr‐69 from the high‐affinity nucleotide and metal binding sites in actin.Biochem. Int.(In press).
10.1016/0167-4838(84)90262-0
10.1093/oxfordjournals.jbchem.a134910
10.1073/pnas.73.8.2742
10.1073/pnas.81.12.3680
10.1016/0024-3205(80)90092-2
10.1073/pnas.78.7.4319
10.1021/bi00527a005
Barden J. A.(1986). Localization of the triphosphate moiety of the bound ATP in actin.Biochim. Biophys. Acta(In press).
10.1111/j.1432-1033.1982.tb05872.x
10.1016/0167-4838(82)90462-9
10.1021/bi00258a020
10.1016/0006-291X(78)90884-7
10.1016/S0021-9258(19)70103-3 / J. Biol. Chem. / 7‐chloro‐4‐nitro‐benzo‐2‐oxa‐1,3‐diazole actin as a probe for actin polymerization by Detmers P. (1981)
10.1016/0014-5793(84)80813-3
10.1021/bi00321a073

Dates

Type	When
Created	20 years, 6 months ago (Feb. 25, 2005, 7:12 a.m.)
Deposited	1 year, 10 months ago (Oct. 21, 2023, 8:01 p.m.)
Indexed	2 days, 19 hours ago (Sept. 4, 2025, 9:28 a.m.)
Issued	39 years, 6 months ago (March 1, 1986)
Published	39 years, 6 months ago (March 1, 1986)
Published Online	20 years, 7 months ago (Feb. 5, 2005)
Published Print	39 years, 6 months ago (March 1, 1986)

Funders 0

None

BibTeX

@article{Hambly_1986, title={Structural and functional domains on actin}, volume={4}, ISSN={1521-1878}, url={http://dx.doi.org/10.1002/bies.950040308}, DOI={10.1002/bies.950040308}, number={3}, journal={BioEssays}, publisher={Wiley}, author={Hambly, Brett D. and Barden, Julian A. and Miki, Masao and Dos Remedios, Cristobal G.}, year={1986}, month=mar, pages={124–128} }

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