DOI: 10.1002/anie.201000048. BioMOFs: Metal–Organic Frameworks for Biological and Medical Applications

BioMOFs: Metal–Organic Frameworks for Biological and Medical Applications

10.1002/anie.201000048

Crossref journal-article

Wiley

Angewandte Chemie International Edition (311)

Abstract

AbstractThe class of highly porous materials called metal–organic frameworks offer many opportunities for applications across biology and medicine. Their wide range of chemical composition makes toxicologically acceptable formulation possible, and their high level of functionality enables possible applications as imaging agents and as delivery vehicles for therapeutic agents. The challenges in the area encompass not only the development of new solids but also improvements in the formulation and processing of the materials, including tailoring the morphology and surface chemistry of the frameworks to fit the proposed applications.

Bibliography

McKinlay, A. C., Morris, R. E., Horcajada, P., FÃ©rey, G., Gref, R., Couvreur, P., & Serre, C. (2010). BioMOFs: MetalâOrganic Frameworks for Biological and Medical Applications. Angewandte Chemie International Edition, 49(36), 6260â6266. Portico.

Authors 7

Alistair C. McKinlay (first)
Russell E. Morris (additional)
Patricia Horcajada (additional)
Gérard Férey (additional)
Ruxandra Gref (additional)
Patrick Couvreur (additional)
Christian Serre (additional)

References 45 Referenced 1,143

10.1039/B618320B
Themed issue: Metal‐organic frameworks Chem. Soc. Rev.2009 38 1201. (10.1039/b906666g)
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10.1002/anie.200703934
Please note that the complex architectures of MOFs are designated by codes such as MIL‐88 MIL‐101 M‐CPO‐27 etc. These codes often originate from the first place of synthesis—for example MIL stands for Material from Institut Lavoisier—and generally define the topological architecture of the materials. A different code indicates different shapes of pores and cavities and often a different chemical composition. For the compounds mentioned in the text the organic linker molecules used are fumarate tetramethylterephthlate and benzene‐1 3 5‐tricarboxylate.
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Dates

Type	When
Created	15 years, 1 month ago (July 22, 2010, 3:06 p.m.)
Deposited	6 months ago (Feb. 23, 2025, 2:24 a.m.)
Indexed	41 minutes ago (Aug. 26, 2025, 8:22 p.m.)
Issued	15 years, 1 month ago (July 22, 2010)
Published	15 years, 1 month ago (July 22, 2010)
Published Online	15 years, 1 month ago (July 22, 2010)
Published Print	15 years ago (Aug. 23, 2010)

Funders 0

None

BibTeX

@article{McKinlay_2010, title={BioMOFs: Metal–Organic Frameworks for Biological and Medical Applications}, volume={49}, ISSN={1521-3773}, url={http://dx.doi.org/10.1002/anie.201000048}, DOI={10.1002/anie.201000048}, number={36}, journal={Angewandte Chemie International Edition}, publisher={Wiley}, author={McKinlay, Alistair C. and Morris, Russell E. and Horcajada, Patricia and Férey, Gérard and Gref, Ruxandra and Couvreur, Patrick and Serre, Christian}, year={2010}, month=jul, pages={6260–6266} }

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