DOI: 10.1002/anie.200502481. Sequential Self‐Assembly of a DNA Hexagon as a Template for the Organization of Gold Nanoparticles

Sequential Self‐Assembly of a DNA Hexagon as a Template for the Organization of Gold Nanoparticles

10.1002/anie.200502481

Crossref journal-article

Wiley

Angewandte Chemie International Edition (311)

Bibliography

Aldaye, F. A., & Sleiman, H. F. (2006). Sequential SelfâAssembly of a DNA Hexagon as a Template for the Organization of Gold Nanoparticles. Angewandte Chemie International Edition, 45(14), 2204â2209. Portico.

Authors 2

Faisal A. Aldaye (first)
Hanadi F. Sleiman (additional)

References 58 Referenced 187

10.1021/jp0039520
10.1146/annurev.physchem.49.1.371
10.1021/la0488351
Examples of extended gold–DNA assemblies:
10.1038/382607a0
10.1021/ja0383367
10.1021/nl048635
10.1021/cr030067f
Discrete gold nanoparticle assemblies:
10.1002/(SICI)1521-3757(19990614)111:12<1925::AID-ANGE1925>3.0.CO;2-2
{'key': 'e_1_2_2_11_3', 'first-page': '808', 'volume': '38', 'year': '1999', 'journal-title': 'Angew. Chem. Int. Ed.'} / Angew. Chem. Int. Ed. (1999)
10.1038/382609a0
10.1002/1521-3757(20011119)113:22<4254::AID-ANGE4254>3.0.CO;2-D
10.1002/1521-3773(20011119)40:22<4128::AID-ANIE4128>3.0.CO;2-S
10.1021/cm0484089
10.1021/ja046747x
10.1021/bi030079v
10.1146/annurev.biophys.27.1.225
10.1021/cr970071p
10.1016/S1367-5931(00)00140-X
10.1002/bip.10531
The self‐assembly of the linear constructs is essentially quantitative. Also the self‐assembly of the DNA hexagon is quite efficient. The isolated yield of the hexagon is 60 % whereas the amount of hexagon in the crude mixture is 75 % (evaluated from UV/Vis spectroscopy). Scale‐up of this synthesis is expected to produce more oligomers if the concentration of DNA is increased. However the yield of the DNA hexagon should not be affected if volumes are increased but similar concentrations of DNA are used.
{'key': 'e_1_2_2_23_2', 'volume-title': 'Supramolecular Chemistry', 'author': 'Steed J. W.', 'year': '2000'} / Supramolecular Chemistry by Steed J. W. (2000)
10.1021/bi00665a020
10.1016/S0021-9258(18)63349-6 / J. Biol. Chem. by Johnson P. H. (1970)
10.1038/nature02307
10.1021/ja031754r
10.1002/ange.19971090116
10.1002/anie.199701111
10.1093/nar/27.15.3035
10.1002/(SICI)1521-3757(19991115)111:22<3513::AID-ANGE3513>3.0.CO;2-7
10.1002/(SICI)1521-3773(19991115)38:22<3311::AID-ANIE3311>3.0.CO;2-2
10.1002/ange.200460255
10.1002/anie.200460255
10.1002/1521-3757(20011217)113:24<4765::AID-ANGE4765>3.0.CO;2-D
10.1002/1521-3773(20011217)40:24<4629::AID-ANIE4629>3.0.CO;2-S
10.1021/ja038333u
10.1021/ja000950k
10.1021/ja0162212
10.1002/ange.200460399
10.1002/anie.200460399
10.1021/ja0483746
{'key': 'e_1_2_2_43_2', 'first-page': '308', 'volume': '4', 'author': 'Hainfeld J. F.', 'year': '1997', 'journal-title': 'Cell Division'} / Cell Division by Hainfeld J. F. (1997)
10.1177/40.2.1552162
{'key': 'e_1_2_2_45_2', 'first-page': '421', 'volume-title': 'Colloidal Gold: Principles, Methods, and Applications,', 'author': 'Beesley J. E.', 'year': '1989'} / Colloidal Gold: Principles, Methods, and Applications, by Beesley J. E. (1989)
The 1:1 ratio of DNA to gold was verified by 1) UV/Vis quantification of a band solely due to the gold particles versus a band due to DNA; 2) titration experiments of the gold–DNA constructs with their complementary partners which showed that a single hybridized product is only obtained at a 1:1 ratio; 3) silver enhancement staining of the bands under conditions where DNA alone does not stain; and 4) significantly reduced band mobility on native agarose gels compared to DNA alone.
{'key': 'e_1_2_2_47_2', 'volume-title': 'Nanoparticles: From Theory to Application', 'author': 'Simon U.', 'year': '2004'} / Nanoparticles: From Theory to Application by Simon U. (2004)
10.1002/1521-4095(200110)13:19<1501::AID-ADMA1501>3.0.CO;2-Z
10.1002/adma.200390134
See Supporting Information. Please also note that molecules2and2 Aushown in Scheme 1 are expected to be conformationally mobile and are only shown as schematic representations.

Dates

Type	When
Created	19 years, 6 months ago (Feb. 27, 2006, 4:20 a.m.)
Deposited	1 year, 10 months ago (Oct. 16, 2023, 1:17 a.m.)
Indexed	4 days, 14 hours ago (Aug. 31, 2025, 6:24 a.m.)
Issued	19 years, 5 months ago (March 17, 2006)
Published	19 years, 5 months ago (March 17, 2006)
Published Online	19 years, 5 months ago (March 17, 2006)
Published Print	19 years, 5 months ago (March 27, 2006)

Funders 0

None

BibTeX

@article{Aldaye_2006, title={Sequential Self‐Assembly of a DNA Hexagon as a Template for the Organization of Gold Nanoparticles}, volume={45}, ISSN={1521-3773}, url={http://dx.doi.org/10.1002/anie.200502481}, DOI={10.1002/anie.200502481}, number={14}, journal={Angewandte Chemie International Edition}, publisher={Wiley}, author={Aldaye, Faisal A. and Sleiman, Hanadi F.}, year={2006}, month=mar, pages={2204–2209} }

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