DOI: 10.1002/anie.199502091. Investigation of Self‐Assembled Supramolecular Species in Solution by IL‐ESMS, a New Mass Spectrometric Technique

Investigation of Self‐Assembled Supramolecular Species in Solution by IL‐ESMS, a New Mass Spectrometric Technique

10.1002/anie.199502091

Crossref journal-article

Wiley

Angewandte Chemie International Edition in English (311)

Abstract

Discrete neutral assemblies in solution can be studied with the analytical method described here. A prerequisite is that one of the components contains an ion‐complexing site, for example a crown ether unit. When alkali metal ions are added, charged assemblies form, which can be examined by electrospray mass spectrometry (ESMS) without disruption of their hydrogen bonds. IL in the title stands for ion labeling.

Bibliography

Russell, K. C., Leize, E., Van Dorsselaer, A., & Lehn, J. (1995). Investigation of SelfâAssembled Supramolecular Species in Solution by ILâESMS, a New Mass Spectrometric Technique. Angewandte Chemie International Edition in English, 34(2), 209â213. Portico.

Authors 4

Keith C. Russell (first)
Emmanuelle Leize (additional)
Alain Van Dorsselaer (additional)
Jean‐Marie Lehn (additional)

References 36 Referenced 97

10.1002/ange.19901021117
10.1002/anie.199013041
10.1126/science.1962191
10.1002/adma.19900020506
10.1073/pnas.90.1.163
10.1002/masy.19930690103
10.1021/ac00149a003
10.1002/mas.1280090103
10.1002/mas.1280100104
10.1126/science.2675315
10.1002/rcm.1290050806
10.1021/ja00169a051
10.1021/ja00010a072
(c)F.Bitsch G.Hegy C. O.Dietrich‐Buchecker E.Leize J.‐P.Sauvage A.Van Dorsselaer New J. Chem.1994 in press.
10.1021/ja00016a069
10.1021/ja00020a085
10.1021/ja00022a058
10.1021/ja00036a066
10.1021/ja00042a046
10.1016/S0040-4039(00)60314-3
10.1016/S0040-4039(00)73558-1
(h)M.Przybylski M. O.Glocker Angew. Chem.1995 in press.
E.Leize A.Van Dorsselaer R.Krämer J.‐M.Lehn J. Chem. Soc. Chem. Commun.1993 990. (10.1039/C39930000990)
S. R.Wilson Q.Lu M. L.Tulchinsky Y.Wu J. Chem. Soc. Chem. Commun.1993 664. (10.1039/c39930000664)
10.1016/S0960-894X(00)80109-2
J.‐M.Lehn M.Mascal A.DeCian J.Fischer J. Chem. Soc. Chem. Commun.1990 479. (10.1039/c39900000479)
10.1021/ja00180a083
10.1021/ja00039a096
10.1002/cber.189903201103
10.1002/jlac.19043350303
CompoundBalso gave satisfactory microanalytical data. TriazinesAandCwere not crystalline and it was not possible to obtain satisfactory microanalyses.
10.1016/1044-0305(90)80006-9
10.1021/ac00002a016
For studies at the rather high concentration (10−2M) used in this work ion‐molecule reactions in the gas phase might occur in the ES source. To be certain that peaks observed for assembliesA3B3 A2B3 andA3B2were not an artifact of ESMS we studied a solution in whichAwas replaced by benzo[18]crown‐6 (18C6) a compound unable to form hydrogen bonds. The only peaks observed in the ES mass spectrum of this solution corresponded to ions 18C6/K+ (18C6)2/K+and (18C6)2/2K+. No peaks for possible assemblies ofBand macrocycle were observed.
The ionization of the complexes in S1was also examined by adding NaClO4and CsCl instead of KPF6. With NaClO4the results were similar to those obtained with KPF6: adducts of KPF6/K+were replaced by adducts of NaClO4/Na+. In contrast with CsCl A3B3was the only complex detected but in two charge states: [A3B3+ 3Cs+] and [A3B3+ 2Cs+]. The difference in the ionization might be explained by the specific complexation of the alkali metal ions by the crown ether. Indeed Cs+is known to form the sandwich complex (18C6)2/Cs+ while Na+and K+give the complexes 18C6/Na+and 18C6/K+.
Interestingly A2B3was present only for large amounts of salt andA3B2only for smaller quantities of salt.

Dates

Type	When
Created	21 years, 7 months ago (Jan. 16, 2004, 9:17 a.m.)
Deposited	1 year, 10 months ago (Oct. 10, 2023, 12:32 p.m.)
Indexed	1 year, 5 months ago (March 16, 2024, 3:50 a.m.)
Issued	30 years, 7 months ago (Feb. 3, 1995)
Published	30 years, 7 months ago (Feb. 3, 1995)
Published Online	21 years, 8 months ago (Dec. 22, 2003)
Published Print	30 years, 7 months ago (Feb. 3, 1995)

Funders 0

None

BibTeX

@article{Russell_1995, title={Investigation of Self‐Assembled Supramolecular Species in Solution by IL‐ESMS, a New Mass Spectrometric Technique}, volume={34}, ISSN={0570-0833}, url={http://dx.doi.org/10.1002/anie.199502091}, DOI={10.1002/anie.199502091}, number={2}, journal={Angewandte Chemie International Edition in English}, publisher={Wiley}, author={Russell, Keith C. and Leize, Emmanuelle and Van Dorsselaer, Alain and Lehn, Jean‐Marie}, year={1995}, month=feb, pages={209–213} }

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