DOI: 10.1002/ana.410170208. Computed tomographic analysis of brain morphometrics in 30 healthy men, aged 21 to 81 years

Computed tomographic analysis of brain morphometrics in 30 healthy men, aged 21 to 81 years

10.1002/ana.410170208

Crossref journal-article

Wiley

Annals of Neurology (311)

Abstract

AbstractComputed transverse axial tomography (CT) was employed to examine brain morphometrics in 30 healthy men, aged 21 to 81 years. Seven consecutive CT slices 30 to 80 mm above the inferior orbitomeatal line were analyzed. CT numbers in grey and white matter regions were not correlated significantly with age (p<0.05), nor were right/left ratios for derived parameters. The volume of gray matter was correlated negatively with age (p>0.05), and the volume of cerebrospinal fluid correlated positively with age, in the seven slices. The volumes of the lateral and third ventricles were elevated in the elderly, and volumes of the thalamus and tenticular nucleus were reduced. The results demonstrate that brain atrophy, evidenced by a loss of grey matter and by dilatation of cerebrospinal fluid spaces, occurs in the healthy elderly, and provide baseline CT‐derived brain morphometric data for healthy men in relation to age.

Bibliography

Schwartz, M., Creasey, H., Grady, C. L., DeLeo, J. M., Frederickson, H. A., Cutler, N. R., & Rapoport, S. I. (1985). Computed tomographic analysis of brain morphometrics in 30 healthy men, aged 21 to 81 years. Annals of Neurology, 17(2), 146â157. Portico.

Authors 7

Michael Schwartz (first)
Helen Creasey (additional)
Cheryl L. Grady (additional)
James M. DeLeo (additional)
Hal A. Frederickson (additional)
Neal R. Cutler (additional)
Stanley I. Rapoport (additional)

References 48 Referenced 109

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Dates

Type	When
Created	20 years, 8 months ago (Jan. 1, 2005, 12:19 p.m.)
Deposited	1 year, 10 months ago (Oct. 20, 2023, 3:08 p.m.)
Indexed	5 days, 18 hours ago (Aug. 27, 2025, 12:12 p.m.)
Issued	40 years, 7 months ago (Feb. 1, 1985)
Published	40 years, 7 months ago (Feb. 1, 1985)
Published Online	20 years, 10 months ago (Oct. 7, 2004)
Published Print	40 years, 7 months ago (Feb. 1, 1985)

Funders 0

None

BibTeX

@article{Schwartz_1985, title={Computed tomographic analysis of brain morphometrics in 30 healthy men, aged 21 to 81 years}, volume={17}, ISSN={1531-8249}, url={http://dx.doi.org/10.1002/ana.410170208}, DOI={10.1002/ana.410170208}, number={2}, journal={Annals of Neurology}, publisher={Wiley}, author={Schwartz, Michael and Creasey, Helen and Grady, Cheryl L. and DeLeo, James M. and Frederickson, Hal A. and Cutler, Neal R. and Rapoport, Stanley I.}, year={1985}, month=feb, pages={146–157} }

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      "date-parts": [
        [
          1985,
          2
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1002/ana.410170208"
  ],
  "URL": "http://dx.doi.org/10.1002/ana.410170208",
  "relation": {},
  "ISSN": [
    "0364-5134",
    "1531-8249"
  ],
  "subject": [],
  "container-title-short": "Annals of Neurology",
  "published": {
    "date-parts": [
      [
        1985,
        2
      ]
    ]
  }
}