DOI: 10.1002/ana.410100209. Some morphometric aspects of the brain in senile dementia of the alzheimer type

Some morphometric aspects of the brain in senile dementia of the alzheimer type

10.1002/ana.410100209

Crossref journal-article

Wiley

Annals of Neurology (311)

Abstract

AbstractImage analysis apparatus was used to count and measure glial and neuronal perikarya in ten size classes in the midfrontal region and superior temporal gyrus of 18 patients with senile dementia of the Alzheimer type for comparison with 12 age‐matched normal specimens. Brain weight was about 8% less in the dementia group. The major differences had to do with larger neurons, which in dementia were reduced by about 40% in the frontal cortex and 46% in the temporal region. The concentration of neuritic plaques did not correlate significantly with brain weight, cortical thickness, or cell counts.

Bibliography

Terry, R. D., Peck, A., DeTeresa, R., Schechter, R., & Horoupian, D. S. (1981). Some morphometric aspects of the brain in senile dementia of the alzheimer type. Annals of Neurology, 10(2), 184â192. Portico.

Authors 5

Robert D. Terry (first)
Arthur Peck (additional)
Richard DeTeresa (additional)
Ruben Schechter (additional)
Dikran S. Horoupian (additional)

References 17 Referenced 657

10.1192/bjp.114.512.797
10.1002/cne.901020206
{'key': 'e_1_2_1_4_2', 'first-page': '345', 'volume-title': "Alzheimer's Disease: Senile Dementia and Related Disorders (Aging", 'author': 'Brody H', 'year': '1978'} / Alzheimer's Disease: Senile Dementia and Related Disorders (Aging by Brody H (1978)
10.1038/288279a0
10.1016/S0140-6736(76)91936-X
10.1016/0306-4522(79)90215-X
10.1016/0022-510X(80)90048-9
10.1073/pnas.76.10.5392
10.1097/00005072-197204000-00006
MatsuyamaH NamickiH WatanabeI:Senile changes in the brain in the Japanese. Incidence of Alzheimer's neurofibrillary change and senile plaques. In Luthy F Bischoff A (eds): Proceedings of the Fifth International Congress of Neuropathology (Excerpta Medica International Congress Series No. 100). Amsterdam Excerpta Medica 1966 pp979–980
10.1016/0006-8993(76)90385-1
10.1002/cne.901550105
10.1097/00005072-198103000-00002
{'key': 'e_1_2_1_15_2', 'first-page': '11', 'volume-title': 'Clinical, Morphologic, and Neurochemical Aspects in the Aging Central Nervous System (Aging', 'author': 'Scheibel ME', 'year': '1975'} / Clinical, Morphologic, and Neurochemical Aspects in the Aging Central Nervous System (Aging by Scheibel ME (1975)
10.1159/000211943
10.1016/0022-510X(70)90063-8
{'key': 'e_1_2_1_18_2', 'first-page': '1', 'volume-title': 'Aging and Dementia', 'author': 'Wang HS', 'year': '1977'} / Aging and Dementia by Wang HS (1977)

Dates

Type	When
Created	20 years, 8 months ago (Jan. 1, 2005, 8:18 a.m.)
Deposited	1 year, 10 months ago (Oct. 7, 2023, 3:29 p.m.)
Indexed	11 hours, 53 minutes ago (Sept. 4, 2025, 9:56 a.m.)
Issued	44 years, 1 month ago (Aug. 1, 1981)
Published	44 years, 1 month ago (Aug. 1, 1981)
Published Online	20 years, 10 months ago (Oct. 7, 2004)
Published Print	44 years, 1 month ago (Aug. 1, 1981)

Funders 0

None

BibTeX

@article{Terry_1981, title={Some morphometric aspects of the brain in senile dementia of the alzheimer type}, volume={10}, ISSN={1531-8249}, url={http://dx.doi.org/10.1002/ana.410100209}, DOI={10.1002/ana.410100209}, number={2}, journal={Annals of Neurology}, publisher={Wiley}, author={Terry, Robert D. and Peck, Arthur and DeTeresa, Richard and Schechter, Ruben and Horoupian, Dikran S.}, year={1981}, month=aug, pages={184–192} }

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