DOI: 10.1002/ana.10106. Localization of autosomal recessive early‐onset parkinsonism to chromosome 1p36 (<i>PARK7</i>) in an independent dataset

Localization of autosomal recessive early‐onset parkinsonism to chromosome 1p36 (PARK7) in an independent dataset

10.1002/ana.10106

Crossref journal-article

Wiley

Annals of Neurology (311)

Abstract

AbstractTwo new loci, PARK6 and PARK7, for autosomal recessive early‐onset parkinsonism have recently been identified on chromosome 1p, in single large pedigrees. Among 4 autosomal recessive early‐onset families analyzed here, 2 supported linkage to PARK7, 1 with conclusive evidence. These data confirm localization of autosomal recessive early‐onset parkinsonism to PARK7, suggesting it to be a frequent locus. Assignment of families to either PARK6 or PARK7 might be difficult because of the proximity of the two loci on chromosome 1p.

Bibliography

Bonifati, V., Breedveld, G. J., Squitieri, F., Vanacore, N., Brustenghi, P., Harhangi, B. S., Montagna, P., Cannella, M., Fabbrini, G., Rizzu, P., van Duijn, C. M., Oostra, B. A., Meco, G., & Heutink, P. (2002). Localization of autosomal recessive earlyâonset parkinsonism to chromosome 1p36 (PARK7) in an independent dataset. Annals of Neurology, 51(2), 253â256. Portico.

Authors 14

Vincenzo Bonifati (first)
Guido J. Breedveld (additional)
Ferdinando Squitieri (additional)
Nicola Vanacore (additional)
Pierluigi Brustenghi (additional)
Biswadjiet S. Harhangi (additional)
Pasquale Montagna (additional)
Milena Cannella (additional)
Giovanni Fabbrini (additional)
Patrizia Rizzu (additional)
Cornelia M. van Duijn (additional)
Ben A. Oostra (additional)
Giuseppe Meco (additional)
Peter Heutink (additional)

References 15 Referenced 59

10.1006/nbdi.2000.0319
10.1001/jama.281.4.341
10.1038/33416
10.1056/NEJM200005253422103
10.1002/1531-8249(200007)48:1<65::AID-ANA10>3.0.CO;2-L
10.1212/WNL.51.3.890
10.1212/WNL.56.4.555
10.1086/319522
10.1086/322996
{'key': 'e_1_2_6_11_2', 'first-page': '388', 'article-title': 'Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction', 'volume': '44', 'author': 'Weber JL', 'year': '1989', 'journal-title': 'Am J Hum Genet'} / Am J Hum Genet / Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction by Weber JL (1989)
10.1126/science.276.5321.2045
10.1038/ng0298-106
{'key': 'e_1_2_6_14_2', 'first-page': '519', 'article-title': 'Rapid multipoint linkage analysis of recessive traits in nuclear families, including homozygosity mapping', 'volume': '56', 'author': 'Kruglyak L', 'year': '1995', 'journal-title': 'Am J Hum Genet'} / Am J Hum Genet / Rapid multipoint linkage analysis of recessive traits in nuclear families, including homozygosity mapping by Kruglyak L (1995)
10.1038/ng1195-241
10.1002/ana.73

Dates

Type	When
Created	23 years ago (Aug. 25, 2002, 6:17 p.m.)
Deposited	1 year, 10 months ago (Oct. 17, 2023, 10:53 a.m.)
Indexed	2 months, 3 weeks ago (June 11, 2025, 11:47 a.m.)
Issued	23 years, 7 months ago (Jan. 31, 2002)
Published	23 years, 7 months ago (Jan. 31, 2002)
Published Online	23 years, 7 months ago (Jan. 31, 2002)
Published Print	23 years, 7 months ago (Feb. 1, 2002)

Funders 0

None

BibTeX

@article{Bonifati_2002, title={Localization of autosomal recessive early‐onset parkinsonism to chromosome 1p36 (PARK7) in an independent dataset}, volume={51}, ISSN={1531-8249}, url={http://dx.doi.org/10.1002/ana.10106}, DOI={10.1002/ana.10106}, number={2}, journal={Annals of Neurology}, publisher={Wiley}, author={Bonifati, Vincenzo and Breedveld, Guido J. and Squitieri, Ferdinando and Vanacore, Nicola and Brustenghi, Pierluigi and Harhangi, Biswadjiet S. and Montagna, Pasquale and Cannella, Milena and Fabbrini, Giovanni and Rizzu, Patrizia and van Duijn, Cornelia M. and Oostra, Ben A. and Meco, Giuseppe and Heutink, Peter}, year={2002}, month=jan, pages={253–256} }

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