DOI: 10.1002/aja.1001620105. Influences of age and vasopressin on the uptake capacity of fluorescent granular perithelial cells (FGP) of small cerebral vessels of the rat

Influences of age and vasopressin on the uptake capacity of fluorescent granular perithelial cells (FGP) of small cerebral vessels of the rat

10.1002/aja.1001620105

Crossref journal-article

Wiley

American Journal of Anatomy (311)

Abstract

AbstractFluorescent granular perithelial cells (FGP) were found in the perivascular space around fine cerebral blood vessels. Their profiles and intracellular inclusions varied with the age of the animals. The FGP are able to take up exogenous substances administered intraventricularly.With light and electron microscopy, the relation between the uptake capacity of FGP and the aging of animals was studied using horseradish peroxidase (HRP). The effects of vasopressin on the uptake of HRP also were examined. The results can be summarized as follows: (1) The uptake capacity of FGP diminished with aging, that is, the reaction product of administered HRP was found abundantly in FGP in young rats, while it was sparse in the FGP of old rats; and (2) vasopressin increased the incorporation of HRP into the FGP of both young and old rats. The possible role of vasopressin in modulating the uptake capacity of FGP is considered, and the differences between FGP and other perivascular cells are discussed.

Bibliography

Mato, M., & Ookawara, S. (1981). Influences of age and vasopressin on the uptake capacity of fluorescent granular perithelial cells (FGP) of small cerebral vessels of the rat. American Journal of Anatomy, 162(1), 45â53. Portico.

Authors 2

Masao Mato (first)
Shigeo Ookawara (additional)

References 14 Referenced 30

10.1097/00005072-196807000-00006
10.1002/aja.1001170204
{'key': 'e_1_2_1_4_1', 'first-page': '376', 'article-title': 'The reaction of pericytes of the central nervous system to exogenous protein', 'volume': '26', 'author': 'Cancilla P. A.', 'year': '1972', 'journal-title': 'Lab. Invest.'} / Lab. Invest. / The reaction of pericytes of the central nervous system to exogenous protein by Cancilla P. A. (1972)
10.1677/joe.0.0410273
10.1159/000145062
10.1097/00005072-196010000-00001
10.1507/endocrj1954.26.239
10.1007/BF01922731
10.1002/aja.1001570308
10.1007/BF01966000
{'key': 'e_1_2_1_12_1', 'first-page': '486', 'article-title': 'Studies on fluorescent granular perithelium (F.G.P.) of rat cerebral cortex ‐ Especially referring to morphological changes in aging', 'volume': '149', 'author': 'Mato M.', 'year': '1981', 'journal-title': 'Anat. Anz.'} / Anat. Anz. / Studies on fluorescent granular perithelium (F.G.P.) of rat cerebral cortex ‐ Especially referring to morphological changes in aging by Mato M. (1981)
10.1016/0006-8993(78)90766-7
10.1016/0006-8993(74)90585-X
10.1007/BF00690695

Dates

Type	When
Created	20 years, 6 months ago (Feb. 26, 2005, 12:53 p.m.)
Deposited	1 year, 10 months ago (Nov. 1, 2023, 8:12 p.m.)
Indexed	2 months ago (July 7, 2025, 2:28 a.m.)
Issued	44 years ago (Sept. 1, 1981)
Published	44 years ago (Sept. 1, 1981)
Published Online	20 years, 7 months ago (Feb. 3, 2005)
Published Print	44 years ago (Sept. 1, 1981)

Funders 0

None

BibTeX

@article{Mato_1981, title={Influences of age and vasopressin on the uptake capacity of fluorescent granular perithelial cells (FGP) of small cerebral vessels of the rat}, volume={162}, ISSN={1553-0795}, url={http://dx.doi.org/10.1002/aja.1001620105}, DOI={10.1002/aja.1001620105}, number={1}, journal={American Journal of Anatomy}, publisher={Wiley}, author={Mato, Masao and Ookawara, Shigeo}, year={1981}, month=sep, pages={45–53} }

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