DOI: 10.1002/adsc.201000663. Ruthenium Pincer‐Catalyzed Acylation of Alcohols Using Esters with Liberation of Hydrogen under Neutral Conditions

Ruthenium Pincer‐Catalyzed Acylation of Alcohols Using Esters with Liberation of Hydrogen under Neutral Conditions

10.1002/adsc.201000663

Crossref journal-article

Wiley

Advanced Synthesis & Catalysis (311)

Abstract

AbstractAcylation of secondary alcohols using non‐activated esters, in particular symmetrical esters (such as ethyl acetate), is achieved under neutral conditions with the liberation of molecular hydrogen. This unprecedented, environmentally benign reaction is homogenously catalyzed by a dearomatized ruthenium pincer PNN complex.

Bibliography

Gnanaprakasam, B., BenâDavid, Y., & Milstein, D. (2010). Ruthenium PincerâCatalyzed Acylation of Alcohols Using Esters with Liberation of Hydrogen under Neutral Conditions. Advanced Synthesis & Catalysis, 352(18), 3169â3173. Portico.

Authors 3

Boopathy Gnanaprakasam (first)
Yehoshoa Ben‐David (additional)
David Milstein (additional)

References 43 Referenced 76

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All of the ethyl acetate has disappeared; due to its volatility some ethyl acetate might have been lost during reflux.
Excess cyclohexanol remained mostly unreacted under the reaction conditions with a small amount of cyclohexanone being formed.

Dates

Type	When
Created	14 years, 8 months ago (Dec. 7, 2010, 11:29 a.m.)
Deposited	1 year, 10 months ago (Oct. 16, 2023, 12:59 p.m.)
Indexed	1 year ago (Aug. 5, 2024, 9:21 p.m.)
Issued	14 years, 8 months ago (Dec. 7, 2010)
Published	14 years, 8 months ago (Dec. 7, 2010)
Published Online	14 years, 8 months ago (Dec. 7, 2010)
Published Print	14 years, 8 months ago (Dec. 17, 2010)

Funders 0

None

BibTeX

@article{Gnanaprakasam_2010, title={Ruthenium Pincer‐Catalyzed Acylation of Alcohols Using Esters with Liberation of Hydrogen under Neutral Conditions}, volume={352}, ISSN={1615-4169}, url={http://dx.doi.org/10.1002/adsc.201000663}, DOI={10.1002/adsc.201000663}, number={18}, journal={Advanced Synthesis & Catalysis}, publisher={Wiley}, author={Gnanaprakasam, Boopathy and Ben‐David, Yehoshoa and Milstein, David}, year={2010}, month=dec, pages={3169–3173} }

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