DOI: 10.1002/adfm.201001329. Gold Nanocages: A Novel Class of Multifunctional Nanomaterials for Theranostic Applications

Gold Nanocages: A Novel Class of Multifunctional Nanomaterials for Theranostic Applications

10.1002/adfm.201001329

Crossref journal-article

Wiley

Advanced Functional Materials (311)

Abstract

AbstractGold nanocages represent a novel class of nanostructures, well‐suited for biomedical applications. They can be readily prepared via the galvanic replacement reaction between silver nanocubes and chloroauric acid. Their optical resonance peaks can be easily and precisely tuned to the near‐infrared region from 650–900 nm, the transparent window for blood and soft tissue. Furthermore, their surface can be conveniently conjugated with various ligands for targeting cancer. In this feature article, we highlight recent advances in the large‐scale synthesis of gold nanocages and their applications in cancer diagnosis and treatment. Specifically, we have scaled up the production of gold nanocages for in vivo studies and evaluated their tumor targeting capabilities. We have also demonstrated their use as contrast agents for photoacoustic tumor imaging and the mapping of sentinel lymph node, as photothermal transducers for cancer treatment, and as smart carriers for controlled release with a near‐infrared laser.

Bibliography

Chen, J., Yang, M., Zhang, Q., Cho, E. C., Cobley, C. M., Kim, C., Glaus, C., Wang, L. V., Welch, M. J., & Xia, Y. (2010). Gold Nanocages: A Novel Class of Multifunctional Nanomaterials for Theranostic Applications. Advanced Functional Materials, 20(21), 3684â3694. Portico.

Authors 10

Jingyi Chen (first)
Miaoxin Yang (additional)
Qiang Zhang (additional)
Eun Chul Cho (additional)
Claire M. Cobley (additional)
Chulhong Kim (additional)
Charles Glaus (additional)
Lihong V. Wang (additional)
Michael J. Welch (additional)
Younan Xia (additional)

References 80 Referenced 211

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a)http://www.cytimmune.com/go.cfm?do=Page.View&pid=19 (accessed: September 2010); b )http://www.nanospectra.com/clinicians/aurolasetherapy.html (accessed: September 2010).

Dates

Type	When
Created	14 years, 10 months ago (Oct. 4, 2010, 9:07 a.m.)
Deposited	5 months, 4 weeks ago (Feb. 26, 2025, 12:33 a.m.)
Indexed	1 month ago (July 20, 2025, 12:24 a.m.)
Issued	14 years, 10 months ago (Oct. 4, 2010)
Published	14 years, 10 months ago (Oct. 4, 2010)
Published Online	14 years, 10 months ago (Oct. 4, 2010)
Published Print	14 years, 9 months ago (Nov. 9, 2010)

Funders 0

None

BibTeX

@article{Chen_2010, title={Gold Nanocages: A Novel Class of Multifunctional Nanomaterials for Theranostic Applications}, volume={20}, ISSN={1616-3028}, url={http://dx.doi.org/10.1002/adfm.201001329}, DOI={10.1002/adfm.201001329}, number={21}, journal={Advanced Functional Materials}, publisher={Wiley}, author={Chen, Jingyi and Yang, Miaoxin and Zhang, Qiang and Cho, Eun Chul and Cobley, Claire M. and Kim, Chulhong and Glaus, Charles and Wang, Lihong V. and Welch, Michael J. and Xia, Younan}, year={2010}, month=oct, pages={3684–3694} }

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