DOI: 10.1002/0471250953.bi1407s23. PharmGKB: An Integrated Resource of Pharmacogenomic Data and Knowledge

PharmGKB: An Integrated Resource of Pharmacogenomic Data and Knowledge

10.1002/0471250953.bi1407s23

Crossref journal-article

Wiley

Current Protocols in Bioinformatics (311)

Abstract

AbstractThe PharmGKB is a publicly available online resource that aims to facilitate understanding how genetic variation contributes to variation in drug response. It is not only a repository of pharmacogenomics primary data, but it also provides fully curated knowledge including drug pathways, annotated pharmacogene summaries, and relationships among genes, drugs, and diseases. This unit describes how to navigate the PharmGKB Web site to retrieve detailed information on genes and important variants, as well as their relationship to drugs and diseases. It also includes protocols on our drug‐centered pathway, annotated pharmacogene summaries, and our Web services for downloading the underlying data. Workflow on how to use PharmGKB to facilitate design of the pharmacogenomic study is also described in this unit. Curr. Protoc. Bioinform. 23:14.7.1‐14.7.17. © 2008 by John Wiley & Sons, Inc.

Bibliography

Gong, L., Owen, R. P., Gor, W., Altman, R. B., & Klein, T. E. (2008). PharmGKB: An Integrated Resource of Pharmacogenomic Data and Knowledge. Current Protocols in Bioinformatics, 23(1). Portico.

Authors 5

Li Gong (first)
Ryan P. Owen (additional)
Winston Gor (additional)
Russ B. Altman (additional)
Teri E. Klein (additional)

References 20 Referenced 21

10.1093/nar/gkj147
10.1038/sj.clpt.6100087
10.1093/nar/gki033
10.1093/nar/gkh036
10.1093/nar/30.1.158
10.1038/sj.clpt.6100048
10.1093/nar/gki072
10.1093/nar/gkh063
10.1038/sj.tpj.6500230
10.1093/nar/gkl928
10.1093/nar/26.1.94
10.1038/sj.clpt.6100099
10.1093/nar/gkl993
10.1038/sj.tpj.6500384
10.1093/nar/gkl842
10.1093/bioinformatics/18.11.1542
{'key': 'e_1_2_8_18_1', 'first-page': '546', 'article-title': 'Drug interactions in cancer therapy', 'volume': '6', 'author': 'Scripture C.D.', 'year': '2006', 'journal-title': 'Nature Rev.'} / Nature Rev. / Drug interactions in cancer therapy by Scripture C.D. (2006)
10.1093/nar/29.1.308
10.1093/nar/gkj067
10.1093/nar/gkj161

Dates

Type	When
Created	16 years, 10 months ago (Oct. 8, 2008, 6 p.m.)
Deposited	2 years ago (Aug. 20, 2023, 9:05 a.m.)
Indexed	5 months ago (March 19, 2025, 12:43 p.m.)
Issued	16 years, 11 months ago (Sept. 1, 2008)
Published	16 years, 11 months ago (Sept. 1, 2008)
Published Online	16 years, 11 months ago (Sept. 1, 2008)
Published Print	16 years, 11 months ago (Sept. 1, 2008)

Funders 0

None

BibTeX

@article{Gong_2008, title={PharmGKB: An Integrated Resource of Pharmacogenomic Data and Knowledge}, volume={23}, ISSN={1934-340X}, url={http://dx.doi.org/10.1002/0471250953.bi1407s23}, DOI={10.1002/0471250953.bi1407s23}, number={1}, journal={Current Protocols in Bioinformatics}, publisher={Wiley}, author={Gong, Li and Owen, Ryan P. and Gor, Winston and Altman, Russ B. and Klein, Teri E.}, year={2008}, month=sep }

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